Quantifying cell cycle-dependent drug sensitivities in cancer using a high throughput synchronisation and screening approach

BACKGROUND: Chemotherapy and targeted agent anti-cancer efficacy is largely dependent on the proliferative state of tumours, as exemplified by agents that target DNA synthesis/replication or mitosis. As a result, cell cycle specificities of a number of cancer drugs are well known. However, they are...

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Detalles Bibliográficos
Autores principales: Johnson, Timothy I., Minteer, Christopher J., Kottmann, Daniel, Dunlop, Charles R., Fernández, Sandra Bernaldo de Quirós, Carnevalli, Larissa S., Wallez, Yann, Lau, Alan, Richards, Frances M., Jodrell, Duncan I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170111/
https://www.ncbi.nlm.nih.gov/pubmed/34049239
http://dx.doi.org/10.1016/j.ebiom.2021.103396

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