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Kinetics of Abacavir-Induced Remodelling of the Major Histocompatibility Complex Class I Peptide Repertoire

Abacavir hypersensitivity syndrome can occur in individuals expressing the HLA-B*57:01 major histocompatibility complex class I allotype when utilising the drug abacavir as a part of their anti-retroviral regimen. The drug is known to bind within the HLA-B*57:01 antigen binding cleft, leading to the...

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Detalles Bibliográficos
Autores principales:	Illing, Patricia T., van Hateren, Andy, Darley, Rachel, Croft, Nathan P., Mifsud, Nicole A., King, Samuel, Kostenko, Lyudmila, Bharadwaj, Mandvi, McCluskey, James, Elliott, Tim, Purcell, Anthony W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170132/ https://www.ncbi.nlm.nih.gov/pubmed/34093574 http://dx.doi.org/10.3389/fimmu.2021.672737

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