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Spontaneous mouse lymphoma in patient-derived tumor xenografts: The importance of systematic analysis of xenografted human tumor tissues in preclinical efficacy trials

Patient-derived tumor xenograft (PDX) is now largely recognized as a key preclinical model for cancer research, mimicking patient tumor phenotype and genotype. Immunodeficient mice, well-known to develop spontaneous lymphoma, are required for PDX growth. As for all animal models used for further cli...

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Detalles Bibliográficos
Autores principales:	Chateau-Joubert, Sophie, Hopfe, Miriam, Richon, Sophie, Decaudin, Didier, Roman-Roman, Sergio, Reyes-Gomez, Edouard, Bieche, Ivan, Nemati, Fariba, Dangles-Marie, Virginie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2021
Materias:	Perspective
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170170/ https://www.ncbi.nlm.nih.gov/pubmed/34051622 http://dx.doi.org/10.1016/j.tranon.2021.101133

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