κ-opioid receptor agonist, U50488H, inhibits pyroptosis through NLRP3 via the Ca(2+)/CaMKII/CREB signaling pathway and improves synaptic plasticity in APP/PS1 mice

Alzheimer's disease (AD) is a progressive neurodegenerative brain disorder with slow onset in most cases. Clinically, dementia associated with AD is characterized by memory disorders, aphasia, executive dysfunction and personality and behavior changes. Currently, treatment strategies attempt to...

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Detalles Bibliográficos
Autores principales: Song, Xiaofu, Cui, Zhiqiang, He, Jiahuan, Yang, Tuo, Sun, Xiaohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170177/
https://www.ncbi.nlm.nih.gov/pubmed/34036389
http://dx.doi.org/10.3892/mmr.2021.12168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170177/
https://www.ncbi.nlm.nih.gov/pubmed/34036389
http://dx.doi.org/10.3892/mmr.2021.12168

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