Glyoxalase 1 and protein kinase Cλ as potential therapeutic targets for late-stage breast cancer

Cancer cells upregulate the expression levels of glycolytic enzymes in order to reach the increased glycolysis required. One such upregulated glycolytic enzyme is glyoxalase 1 (GLO 1), which catalyzes the conversion of toxic methylglyoxal to nontoxic S-D-lactoylglutathione. Protein kinase Cλ (PKCλ)...

Descripción completa

Detalles Bibliográficos
Autores principales: Motomura, Hitomi, Ozaki, Ayaka, Tamori, Shoma, Onaga, Chotaro, Nozaki, Yuka, Waki, Yuko, Takasawa, Ryoko, Yoshizawa, Kazumi, Mano, Yasunari, Sato, Tsugumichi, Sasaki, Kazunori, Ishiguro, Hitoshi, Miyagi, Yohei, Nagashima, Yoji, Yamamoto, Kouji, Sato, Keiko, Hanawa, Takehisa, Tanuma, Sei-Ichi, Ohno, Shigeo, Akimoto, Kazunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170180/
https://www.ncbi.nlm.nih.gov/pubmed/34093768
http://dx.doi.org/10.3892/ol.2021.12808

Ejemplares similares

Ejemplares similares