Full-length ORF2 sequence-based genetic and phylogenetic characterization of Korean feline caliciviruses

Feline calicivirus (FCV) is a highly infectious pathogen in cats and widely distributed worldwide with high genetic variation. Full-length open reading frame 2 of 5 from recently isolated Korean FCV isolates were sequenced and compared with those of global isolates. The results of phylogenetic analy...

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Autores principales: Kim, Sung Jae, Kim, Cheongung, Chung, Hee Chun, Park, Yong Ho, Park, Kun Taek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Veterinary Science 2021
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170210/
https://www.ncbi.nlm.nih.gov/pubmed/33908206
http://dx.doi.org/10.4142/jvs.2021.22.e32
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author Kim, Sung Jae
Kim, Cheongung
Chung, Hee Chun
Park, Yong Ho
Park, Kun Taek
author_facet Kim, Sung Jae
Kim, Cheongung
Chung, Hee Chun
Park, Yong Ho
Park, Kun Taek
author_sort Kim, Sung Jae
collection PubMed
description Feline calicivirus (FCV) is a highly infectious pathogen in cats and widely distributed worldwide with high genetic variation. Full-length open reading frame 2 of 5 from recently isolated Korean FCV isolates were sequenced and compared with those of global isolates. The results of phylogenetic analysis supported dividing global FCV isolates into two genogroups (type I and II) and demonstrated the presence of genogroup II in Korea, indicating their geographic spread in East Asia. High sequence variations in region E of the FCV isolates emphasizes that a novel vaccine needs to be developed to induce protective immunity against various FCV strains.
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spelling pubmed-81702102021-06-04 Full-length ORF2 sequence-based genetic and phylogenetic characterization of Korean feline caliciviruses Kim, Sung Jae Kim, Cheongung Chung, Hee Chun Park, Yong Ho Park, Kun Taek J Vet Sci Rapid Communication Feline calicivirus (FCV) is a highly infectious pathogen in cats and widely distributed worldwide with high genetic variation. Full-length open reading frame 2 of 5 from recently isolated Korean FCV isolates were sequenced and compared with those of global isolates. The results of phylogenetic analysis supported dividing global FCV isolates into two genogroups (type I and II) and demonstrated the presence of genogroup II in Korea, indicating their geographic spread in East Asia. High sequence variations in region E of the FCV isolates emphasizes that a novel vaccine needs to be developed to induce protective immunity against various FCV strains. The Korean Society of Veterinary Science 2021-05 2021-03-18 /pmc/articles/PMC8170210/ /pubmed/33908206 http://dx.doi.org/10.4142/jvs.2021.22.e32 Text en © 2021 The Korean Society of Veterinary Science https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Rapid Communication
Kim, Sung Jae
Kim, Cheongung
Chung, Hee Chun
Park, Yong Ho
Park, Kun Taek
Full-length ORF2 sequence-based genetic and phylogenetic characterization of Korean feline caliciviruses
title Full-length ORF2 sequence-based genetic and phylogenetic characterization of Korean feline caliciviruses
title_full Full-length ORF2 sequence-based genetic and phylogenetic characterization of Korean feline caliciviruses
title_fullStr Full-length ORF2 sequence-based genetic and phylogenetic characterization of Korean feline caliciviruses
title_full_unstemmed Full-length ORF2 sequence-based genetic and phylogenetic characterization of Korean feline caliciviruses
title_short Full-length ORF2 sequence-based genetic and phylogenetic characterization of Korean feline caliciviruses
title_sort full-length orf2 sequence-based genetic and phylogenetic characterization of korean feline caliciviruses
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170210/
https://www.ncbi.nlm.nih.gov/pubmed/33908206
http://dx.doi.org/10.4142/jvs.2021.22.e32
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