The Usefulness of a Transbronchial Lung Cryobiopsy for Diffuse Bronchiolitis

We herein report four cases of diffuse bronchiolitis proven by a transbronchial lung cryobiopsy (TBLC). Based on various aspects, including the pathological findings, we definitively diagnosed two patients with diffuse panbronchiolitis (DPB) and the other two with primary ciliary dyskinesia (PCD). O...

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Autores principales: Yamakawa, Hideaki, Takemura, Tamiko, Sato, Shintaro, Nakamura, Tomohiko, Nishizawa, Tomotaka, Oba, Tomohiro, Kawabe, Rie, Akasaka, Keiichi, Amano, Masako, Kuwano, Kazuyoshi, Matsushima, Hidekazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170248/
https://www.ncbi.nlm.nih.gov/pubmed/33281160
http://dx.doi.org/10.2169/internalmedicine.6028-20
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author Yamakawa, Hideaki
Takemura, Tamiko
Sato, Shintaro
Nakamura, Tomohiko
Nishizawa, Tomotaka
Oba, Tomohiro
Kawabe, Rie
Akasaka, Keiichi
Amano, Masako
Kuwano, Kazuyoshi
Matsushima, Hidekazu
author_facet Yamakawa, Hideaki
Takemura, Tamiko
Sato, Shintaro
Nakamura, Tomohiko
Nishizawa, Tomotaka
Oba, Tomohiro
Kawabe, Rie
Akasaka, Keiichi
Amano, Masako
Kuwano, Kazuyoshi
Matsushima, Hidekazu
author_sort Yamakawa, Hideaki
collection PubMed
description We herein report four cases of diffuse bronchiolitis proven by a transbronchial lung cryobiopsy (TBLC). Based on various aspects, including the pathological findings, we definitively diagnosed two patients with diffuse panbronchiolitis (DPB) and the other two with primary ciliary dyskinesia (PCD). One of the DPB patients had more severe peribronchiolar fibrosis than the other, and the disease course was refractory to macrolide therapy. One of the PCD patients was additionally diagnosed with combined constrictive bronchiolitis. This report highlights the importance of a TBLC in the differentiation of bronchiolitis, suggesting its utility for helping pulmonologists formulate a treatment strategy.
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spelling pubmed-81702482021-06-11 The Usefulness of a Transbronchial Lung Cryobiopsy for Diffuse Bronchiolitis Yamakawa, Hideaki Takemura, Tamiko Sato, Shintaro Nakamura, Tomohiko Nishizawa, Tomotaka Oba, Tomohiro Kawabe, Rie Akasaka, Keiichi Amano, Masako Kuwano, Kazuyoshi Matsushima, Hidekazu Intern Med Case Report We herein report four cases of diffuse bronchiolitis proven by a transbronchial lung cryobiopsy (TBLC). Based on various aspects, including the pathological findings, we definitively diagnosed two patients with diffuse panbronchiolitis (DPB) and the other two with primary ciliary dyskinesia (PCD). One of the DPB patients had more severe peribronchiolar fibrosis than the other, and the disease course was refractory to macrolide therapy. One of the PCD patients was additionally diagnosed with combined constrictive bronchiolitis. This report highlights the importance of a TBLC in the differentiation of bronchiolitis, suggesting its utility for helping pulmonologists formulate a treatment strategy. The Japanese Society of Internal Medicine 2020-12-07 2021-05-01 /pmc/articles/PMC8170248/ /pubmed/33281160 http://dx.doi.org/10.2169/internalmedicine.6028-20 Text en Copyright © 2021 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Yamakawa, Hideaki
Takemura, Tamiko
Sato, Shintaro
Nakamura, Tomohiko
Nishizawa, Tomotaka
Oba, Tomohiro
Kawabe, Rie
Akasaka, Keiichi
Amano, Masako
Kuwano, Kazuyoshi
Matsushima, Hidekazu
The Usefulness of a Transbronchial Lung Cryobiopsy for Diffuse Bronchiolitis
title The Usefulness of a Transbronchial Lung Cryobiopsy for Diffuse Bronchiolitis
title_full The Usefulness of a Transbronchial Lung Cryobiopsy for Diffuse Bronchiolitis
title_fullStr The Usefulness of a Transbronchial Lung Cryobiopsy for Diffuse Bronchiolitis
title_full_unstemmed The Usefulness of a Transbronchial Lung Cryobiopsy for Diffuse Bronchiolitis
title_short The Usefulness of a Transbronchial Lung Cryobiopsy for Diffuse Bronchiolitis
title_sort usefulness of a transbronchial lung cryobiopsy for diffuse bronchiolitis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170248/
https://www.ncbi.nlm.nih.gov/pubmed/33281160
http://dx.doi.org/10.2169/internalmedicine.6028-20
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