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Successful Treatment with Benralizumab for Allergic Bronchopulmonary Aspergillosis That Developed after Disastrous Heavy Rainfall in Western Japan

We herein report a 56-year-old woman who developed allergic bronchopulmonary aspergillosis (ABPA) possibly due to fungal exposure after disastrous heavy rainfall in Western Japan in 2018. She was diagnosed with ABPA complicated with asthma, increased peripheral blood eosinophil count, elevation of s...

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Autores principales: Matsuura, Hiroaki, Fujiwara, Keiichi, Omori, Hiroki, Onishi, Kiriko, Kuribayashi, Tadahiro, Mitsumune, Sho, Takigawa, Yuki, Kudo, Kenichiro, Minami, Daisuke, Sato, Akiko, Sato, Ken, Shibayama, Takuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170259/
https://www.ncbi.nlm.nih.gov/pubmed/33191330
http://dx.doi.org/10.2169/internalmedicine.6217-20
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author Matsuura, Hiroaki
Fujiwara, Keiichi
Omori, Hiroki
Onishi, Kiriko
Kuribayashi, Tadahiro
Mitsumune, Sho
Takigawa, Yuki
Kudo, Kenichiro
Minami, Daisuke
Sato, Akiko
Sato, Ken
Shibayama, Takuo
author_facet Matsuura, Hiroaki
Fujiwara, Keiichi
Omori, Hiroki
Onishi, Kiriko
Kuribayashi, Tadahiro
Mitsumune, Sho
Takigawa, Yuki
Kudo, Kenichiro
Minami, Daisuke
Sato, Akiko
Sato, Ken
Shibayama, Takuo
author_sort Matsuura, Hiroaki
collection PubMed
description We herein report a 56-year-old woman who developed allergic bronchopulmonary aspergillosis (ABPA) possibly due to fungal exposure after disastrous heavy rainfall in Western Japan in 2018. She was diagnosed with ABPA complicated with asthma, increased peripheral blood eosinophil count, elevation of specific immunoglobulin E for Aspergillus fumigatus, positive Aspergillus fumigatus precipitation antibody reaction test results, and notable chest computed tomography findings. After treatment with benralizumab, her symptoms, peripheral blood eosinophil count, radiological findings, and respiratory function dramatically improved. The administration of benralizumab appears to be an effective treatment strategy for ABPA.
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spelling pubmed-81702592021-06-11 Successful Treatment with Benralizumab for Allergic Bronchopulmonary Aspergillosis That Developed after Disastrous Heavy Rainfall in Western Japan Matsuura, Hiroaki Fujiwara, Keiichi Omori, Hiroki Onishi, Kiriko Kuribayashi, Tadahiro Mitsumune, Sho Takigawa, Yuki Kudo, Kenichiro Minami, Daisuke Sato, Akiko Sato, Ken Shibayama, Takuo Intern Med Case Report We herein report a 56-year-old woman who developed allergic bronchopulmonary aspergillosis (ABPA) possibly due to fungal exposure after disastrous heavy rainfall in Western Japan in 2018. She was diagnosed with ABPA complicated with asthma, increased peripheral blood eosinophil count, elevation of specific immunoglobulin E for Aspergillus fumigatus, positive Aspergillus fumigatus precipitation antibody reaction test results, and notable chest computed tomography findings. After treatment with benralizumab, her symptoms, peripheral blood eosinophil count, radiological findings, and respiratory function dramatically improved. The administration of benralizumab appears to be an effective treatment strategy for ABPA. The Japanese Society of Internal Medicine 2020-11-16 2021-05-01 /pmc/articles/PMC8170259/ /pubmed/33191330 http://dx.doi.org/10.2169/internalmedicine.6217-20 Text en Copyright © 2021 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Matsuura, Hiroaki
Fujiwara, Keiichi
Omori, Hiroki
Onishi, Kiriko
Kuribayashi, Tadahiro
Mitsumune, Sho
Takigawa, Yuki
Kudo, Kenichiro
Minami, Daisuke
Sato, Akiko
Sato, Ken
Shibayama, Takuo
Successful Treatment with Benralizumab for Allergic Bronchopulmonary Aspergillosis That Developed after Disastrous Heavy Rainfall in Western Japan
title Successful Treatment with Benralizumab for Allergic Bronchopulmonary Aspergillosis That Developed after Disastrous Heavy Rainfall in Western Japan
title_full Successful Treatment with Benralizumab for Allergic Bronchopulmonary Aspergillosis That Developed after Disastrous Heavy Rainfall in Western Japan
title_fullStr Successful Treatment with Benralizumab for Allergic Bronchopulmonary Aspergillosis That Developed after Disastrous Heavy Rainfall in Western Japan
title_full_unstemmed Successful Treatment with Benralizumab for Allergic Bronchopulmonary Aspergillosis That Developed after Disastrous Heavy Rainfall in Western Japan
title_short Successful Treatment with Benralizumab for Allergic Bronchopulmonary Aspergillosis That Developed after Disastrous Heavy Rainfall in Western Japan
title_sort successful treatment with benralizumab for allergic bronchopulmonary aspergillosis that developed after disastrous heavy rainfall in western japan
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170259/
https://www.ncbi.nlm.nih.gov/pubmed/33191330
http://dx.doi.org/10.2169/internalmedicine.6217-20
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