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Successful Treatment with Benralizumab for Allergic Bronchopulmonary Aspergillosis That Developed after Disastrous Heavy Rainfall in Western Japan
We herein report a 56-year-old woman who developed allergic bronchopulmonary aspergillosis (ABPA) possibly due to fungal exposure after disastrous heavy rainfall in Western Japan in 2018. She was diagnosed with ABPA complicated with asthma, increased peripheral blood eosinophil count, elevation of s...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japanese Society of Internal Medicine
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170259/ https://www.ncbi.nlm.nih.gov/pubmed/33191330 http://dx.doi.org/10.2169/internalmedicine.6217-20 |
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author | Matsuura, Hiroaki Fujiwara, Keiichi Omori, Hiroki Onishi, Kiriko Kuribayashi, Tadahiro Mitsumune, Sho Takigawa, Yuki Kudo, Kenichiro Minami, Daisuke Sato, Akiko Sato, Ken Shibayama, Takuo |
author_facet | Matsuura, Hiroaki Fujiwara, Keiichi Omori, Hiroki Onishi, Kiriko Kuribayashi, Tadahiro Mitsumune, Sho Takigawa, Yuki Kudo, Kenichiro Minami, Daisuke Sato, Akiko Sato, Ken Shibayama, Takuo |
author_sort | Matsuura, Hiroaki |
collection | PubMed |
description | We herein report a 56-year-old woman who developed allergic bronchopulmonary aspergillosis (ABPA) possibly due to fungal exposure after disastrous heavy rainfall in Western Japan in 2018. She was diagnosed with ABPA complicated with asthma, increased peripheral blood eosinophil count, elevation of specific immunoglobulin E for Aspergillus fumigatus, positive Aspergillus fumigatus precipitation antibody reaction test results, and notable chest computed tomography findings. After treatment with benralizumab, her symptoms, peripheral blood eosinophil count, radiological findings, and respiratory function dramatically improved. The administration of benralizumab appears to be an effective treatment strategy for ABPA. |
format | Online Article Text |
id | pubmed-8170259 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | The Japanese Society of Internal Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-81702592021-06-11 Successful Treatment with Benralizumab for Allergic Bronchopulmonary Aspergillosis That Developed after Disastrous Heavy Rainfall in Western Japan Matsuura, Hiroaki Fujiwara, Keiichi Omori, Hiroki Onishi, Kiriko Kuribayashi, Tadahiro Mitsumune, Sho Takigawa, Yuki Kudo, Kenichiro Minami, Daisuke Sato, Akiko Sato, Ken Shibayama, Takuo Intern Med Case Report We herein report a 56-year-old woman who developed allergic bronchopulmonary aspergillosis (ABPA) possibly due to fungal exposure after disastrous heavy rainfall in Western Japan in 2018. She was diagnosed with ABPA complicated with asthma, increased peripheral blood eosinophil count, elevation of specific immunoglobulin E for Aspergillus fumigatus, positive Aspergillus fumigatus precipitation antibody reaction test results, and notable chest computed tomography findings. After treatment with benralizumab, her symptoms, peripheral blood eosinophil count, radiological findings, and respiratory function dramatically improved. The administration of benralizumab appears to be an effective treatment strategy for ABPA. The Japanese Society of Internal Medicine 2020-11-16 2021-05-01 /pmc/articles/PMC8170259/ /pubmed/33191330 http://dx.doi.org/10.2169/internalmedicine.6217-20 Text en Copyright © 2021 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Matsuura, Hiroaki Fujiwara, Keiichi Omori, Hiroki Onishi, Kiriko Kuribayashi, Tadahiro Mitsumune, Sho Takigawa, Yuki Kudo, Kenichiro Minami, Daisuke Sato, Akiko Sato, Ken Shibayama, Takuo Successful Treatment with Benralizumab for Allergic Bronchopulmonary Aspergillosis That Developed after Disastrous Heavy Rainfall in Western Japan |
title | Successful Treatment with Benralizumab for Allergic Bronchopulmonary Aspergillosis That Developed after Disastrous Heavy Rainfall in Western Japan |
title_full | Successful Treatment with Benralizumab for Allergic Bronchopulmonary Aspergillosis That Developed after Disastrous Heavy Rainfall in Western Japan |
title_fullStr | Successful Treatment with Benralizumab for Allergic Bronchopulmonary Aspergillosis That Developed after Disastrous Heavy Rainfall in Western Japan |
title_full_unstemmed | Successful Treatment with Benralizumab for Allergic Bronchopulmonary Aspergillosis That Developed after Disastrous Heavy Rainfall in Western Japan |
title_short | Successful Treatment with Benralizumab for Allergic Bronchopulmonary Aspergillosis That Developed after Disastrous Heavy Rainfall in Western Japan |
title_sort | successful treatment with benralizumab for allergic bronchopulmonary aspergillosis that developed after disastrous heavy rainfall in western japan |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170259/ https://www.ncbi.nlm.nih.gov/pubmed/33191330 http://dx.doi.org/10.2169/internalmedicine.6217-20 |
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