Cargando…
FUT8-AS1 Inhibits the Malignancy of Melanoma Through Promoting miR-145-5p Biogenesis and Suppressing NRAS/MAPK Signaling
Melanoma is the major lethal skin malignancy. However, the critical molecular drivers governing melanoma progression and prognosis are still not clear. By analyzing The Cancer Genome Atlas (TCGA) data, we identified FUT8-AS1 as a prognosis-related long non-coding RNA (lncRNA) in melanoma. We further...
Autores principales: | Chen, Xiang-jun, Liu, Sha, Han, Dong-mei, Han, De-zhi, Sun, Wei-jing, Zhao, Xiao-chun, Liang, Jun-qing, Yu, Li |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170315/ https://www.ncbi.nlm.nih.gov/pubmed/34094894 http://dx.doi.org/10.3389/fonc.2020.586085 |
Ejemplares similares
-
Regulation of melanoma malignancy by the RP11-705C15.3/miR-145-5p/NRAS/MAPK signaling axis
por: Chen, Xiang-jun, et al.
Publicado: (2020) -
Effects of miR‐145‐5p through NRAS on the cell proliferation, apoptosis, migration, and invasion in melanoma by inhibiting MAPK and PI3K/AKT pathways
por: Liu, Sha, et al.
Publicado: (2017) -
cFUT8 promotes liver cancer progression by miR-548c/FUT8 axis
por: Li, Chong, et al.
Publicado: (2021) -
Case report: Therapeutic potential of T-VEC in combination with MEK inhibitors in melanoma patients with NRAS mutation
por: Simon, Sonja C. S., et al.
Publicado: (2023) -
Loss of miR-143 and miR-145 in condyloma acuminatum promotes cellular proliferation and inhibits apoptosis by targeting NRAS
por: Liu, Xiaoyan, et al.
Publicado: (2018)