Cargando…

Antimicrobial Peptides SLPI and Beta Defensin-1 in Sputum are Negatively Correlated with FEV(1)

BACKGROUND: Chronic obstructive pulmonary disease (COPD) and asthma have heterogeneous inflammation with inhaled corticosteroids (ICS) as a mainstay of treatment. There is increased prevalence of non-typeable Haemophilus influenzae (NTHi) persistence in airways of patients with neutrophilic airway i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cane, Jennifer, Tregidgo, Laura, Thulborn, Samantha, Finch, Donna, Bafadhel, Mona
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170372/ https://www.ncbi.nlm.nih.gov/pubmed/34093009 http://dx.doi.org/10.2147/COPD.S301622

Ejemplares similares

Molecular Diversity of the Antimicrobial Domain of Beta-Defensin 3 and Homologous Peptides
por: Nava, Gerardo M., et al.
Publicado: (2009)

Detection of Cell-Dissociated Non-Typeable Haemophilus influenzae in the Airways of Patients with Chronic Obstructive Pulmonary Disease
por: Thulborn, Samantha J, et al.
Publicado: (2020)

Isolation of filamentous fungi from sputum in asthma is associated with reduced post-bronchodilator FEV(1)
por: Agbetile, J, et al.
Publicado: (2012)

Sputum eosinophilia is a determinant of FEV1 decline in occupational asthma: results of an observational study
por: Talini, Donatella, et al.
Publicado: (2015)

Sputum cell counts to manage prednisone-dependent asthma: effects on FEV(1) and eosinophilic exacerbations
por: Aziz-Ur-Rehman, Afia, et al.
Publicado: (2017)

How SLPI soothes
por: Van Epps, Heather L.
Publicado: (2005)

Expression and Antimicrobial Function of Beta-Defensin 1 in the Lower Urinary Tract
por: Becknell, Brian, et al.
Publicado: (2013)

The First Salamander Defensin Antimicrobial Peptide
por: Meng, Ping, et al.
Publicado: (2013)

Defensins and Other Antimicrobial Peptides and Proteins
por: Lehrer, Robert I., et al.
Publicado: (2005)

Activity of sputum p38 MAPK is correlated with airway inflammation and reduced FEV(1) in COPD patients
por: Huang, Cuiping, et al.
Publicado: (2013)

Expression and Functional Characterization of a Novel Antimicrobial Peptide: Human Beta-Defensin 118
por: Lin, Qian, et al.
Publicado: (2020)

Low human beta-defensin-2 levels in the sputum of COPD patients are associated with the risk of exacerbations
por: Feng, Shengchuan, et al.
Publicado: (2023)

Complex of human neutrophil elastase with 1/2SLPI
por: Koizumi, Masahiro, et al.
Publicado: (2008)

Reliability of FEV(1)/FEV(6) to Diagnose Airflow Obstruction Compared with FEV(1)/FVC: The PLATINO Longitudinal Study
por: Perez-Padilla, Rogelio, et al.
Publicado: (2013)

Antimicrobial peptide β-defensin-1 expression is upregulated in Alzheimer’s brain
por: Williams, Wesley M, et al.
Publicado: (2013)

Fixed Cut-Off for FEV1/FEV6 and FEV6 in Detection of Obstructive and Restrictive Patterns
por: Aghili, Rokhsareh, et al.
Publicado: (2013)

Production of secretory leucocyte protease inhibitor (SLPI) in human pancreatic beta-cells.
por: Nyström, M, et al.
Publicado: (1999)

A Novel Beta-Defensin Antimicrobial Peptide in Atlantic Cod with Stimulatory Effect on Phagocytic Activity
por: Ruangsri, Jareeporn, et al.
Publicado: (2013)

Beta-defensin derived cationic antimicrobial peptides with potent killing activity against gram negative and gram positive bacteria
por: Yang, Ming, et al.
Publicado: (2018)

The Antimicrobial Peptide Human Beta-Defensin-3 Is Induced by Platelet-Released Growth Factors in Primary Keratinocytes
por: Bayer, Andreas, et al.
Publicado: (2017)

Neutrophil elastase as a biomarker for bacterial infection in COPD
por: Thulborn, Samantha J., et al.
Publicado: (2019)

Cut-off value of FEV(1)/FEV(6) as a surrogate for FEV(1)/FVC for detecting airway obstruction in a Korean population
por: Chung, Kyung Soo, et al.
Publicado: (2016)

Antimicrobial Activity of Snake β-Defensins and Derived Peptides
por: Oguiura, Nancy, et al.
Publicado: (2021)

Implications of Human Antimicrobial Peptide Defensin Beta-1 in Clinical Oral Squamous Cell Carcinoma Patients via an Integrated Bioinformatics Approach
por: Li, Simin, et al.
Publicado: (2022)

Andrographolide and 4-Phenylbutyric Acid Administration Increase the Expression of Antimicrobial Peptides Beta-Defensin-1 and Cathelicidin and Reduce Mortality in Murine Sepsis
por: Bolatchiev, Albert, et al.
Publicado: (2022)

Structure basis 1/2SLPI and porcine pancreas trypsin interaction
por: Fukushima, Kei, et al.
Publicado: (2013)

Expressions of Antimicrobial Peptides LL-37, Human Beta Defensin-2 and -3 in the Lesions of Cutaneous Tuberculosis and Tuberculids
por: Zhao, Zheng, et al.
Publicado: (2016)

Antimicrobial Peptides: Identification of two Beta-Defensins in a Teleost Fish, the European Sea Bass (Dicentrarchus labrax)
por: Barroso, Carolina, et al.
Publicado: (2021)

Cementoin–SLPI fusion protein binds to human monocytes and epithelial cells and shows higher biological activity than SLPI
por: Maffía, Paulo C., et al.
Publicado: (2018)

Genome organization and molecular characterization of the three Formica exsecta viruses—FeV1, FeV2 and FeV4
por: Dhaygude, Kishor, et al.
Publicado: (2019)

Defensins knowledgebase: a manually curated database and information source focused on the defensins family of antimicrobial peptides
por: Seebah, Shalin, et al.
Publicado: (2007)

Antimicrobial Characterization of Site-Directed Mutagenesis of Porcine Beta Defensin 2
por: Huang, Xian-xian, et al.
Publicado: (2015)

Investigating the role of pentraxin 3 as a biomarker for bacterial infection in subjects with COPD
por: Thulborn, Samantha J, et al.
Publicado: (2017)

SLPI: a new target for stopping metastasis
por: Munn, Lance L., et al.
Publicado: (2018)

Utility of FEV(1)/FEV(6) index in patients with multimorbidity hospitalized for decompensation of chronic diseases
por: Komal, Shakeel, et al.
Publicado: (2019)

Ciprofloxacin Affects Host Cells by Suppressing Expression of the Endogenous Antimicrobial Peptides Cathelicidins and Beta-Defensin-3 in Colon Epithelia
por: Sarker, Protim, et al.
Publicado: (2014)

The Antimicrobial Peptide Human Beta-Defensin 2 Inhibits Biofilm Production of Pseudomonas aeruginosa Without Compromising Metabolic Activity
por: Parducho, Kevin R., et al.
Publicado: (2020)

Forced Expiratory Volume in 6 s (FEV(6)) and FEV(1)/FEV(6) Values as a Viable Alternative for Forced Vital Capacity (FVC) and FEV(1)/FVC Values During Pregnancy in South East Nigeria: A Preliminary Study
por: Nwagha, U, et al.
Publicado: (2014)

Paneth cell α-defensin 6 (HD-6) is an antimicrobial peptide
por: Schroeder, B O, et al.
Publicado: (2015)

PvD(1) defensin, a plant antimicrobial peptide with inhibitory activity against Leishmania amazonensis
por: do Nascimento, Viviane V., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_7s8mepv0b70i8hl22psl7tomkr