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Down-Regulation of Inpp5e Associated With Abnormal Ciliogenesis During Embryonic Neurodevelopment Under Inositol Deficiency

The inositol polyphosphate-5-phosphatase E (Inpp5e) gene is located on chromosome 9q34.3. The enzyme it encodes mainly hydrolyzes the 5-phosphate groups of phosphatidylinositol (3,4,5)-trisphosphate (PtdIns (3,4,5) P3) and phosphatidylinositol (4,5)-bisphosphate (PtdIns (4,5)P2), which are closely r...

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Detalles Bibliográficos
Autores principales:	Yue, Huixuan, Li, Shen, Qin, Jiaxing, Gao, Tingting, Lyu, Jianjun, Liu, Yu, Wang, Xiuwei, Guan, Zhen, Zhu, Zhiqiang, Niu, Bo, Zhong, Rugang, Guo, Jin, Wang, Jianhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Neurology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170399/ https://www.ncbi.nlm.nih.gov/pubmed/34093381 http://dx.doi.org/10.3389/fneur.2021.579998

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