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Yap1-2 Isoform Is the Primary Mediator in TGF-β1 Induced EMT in Pancreatic Cancer
Pancreatic ductal adenocarcinoma (PDAC) is the most aggressive human malignancy and intrinsically resistant to conventional therapies. YAP1, as a key downstream effector of the Hippo pathway, plays an important role in tumorigenesis including PDAC. Alternative mRNA splicing of YAP1 results in at lea...
Autores principales: | Gao, Chao, Quan, Mei-Yu, Chen, Qian-Jie, Yang, Ruo, Wu, Yuanyuan, Liu, Jia-Yu, Lin, Zhong-Yuan, Li, Xue, Cai, Jue-Ting, Jiang, Tian-Fang, Xu, Le, Mossahebi-Mohammadi, Majid, Guo, Qiang, Zhang, Jin-San |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170464/ https://www.ncbi.nlm.nih.gov/pubmed/34094936 http://dx.doi.org/10.3389/fonc.2021.649290 |
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