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SDHB Suppresses the Tumorigenesis and Development of ccRCC by Inhibiting Glycolysis

Metabolic reprogramming is the prominent feature of clear cell renal cell carcinoma (ccRCC). Succinate dehydrogenase subunit B (SDHB) is one of subunits of mitochondrial respiratory chain complex II. The loss of SDHB function is closely related with metabolic changes in kidney cancer cells. However,...

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Detalles Bibliográficos
Autores principales: Fang, Zhiyu, Sun, Qiang, Yang, Huihui, Zheng, Junfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170479/
https://www.ncbi.nlm.nih.gov/pubmed/34094922
http://dx.doi.org/10.3389/fonc.2021.639408