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Individuals with schizophrenia who act violently towards others profit unequally from inpatient treatment—Identifying subgroups by latent class analysis

BACKGROUND: People with schizophrenia show a higher risk of committing violent offenses. Previous studies indicate that there are at least three subtypes of offenders with schizophrenia. OBJECTIVES: Employing latent class analysis, the goals of this study were to investigate the presence of homogene...

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Autores principales: Kirchebner, Johannes, Lau, Steffen, Kling, Sabine, Sonnweber, Martina, Günther, Moritz Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170574/
https://www.ncbi.nlm.nih.gov/pubmed/33320399
http://dx.doi.org/10.1002/mpr.1856
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author Kirchebner, Johannes
Lau, Steffen
Kling, Sabine
Sonnweber, Martina
Günther, Moritz Philipp
author_facet Kirchebner, Johannes
Lau, Steffen
Kling, Sabine
Sonnweber, Martina
Günther, Moritz Philipp
author_sort Kirchebner, Johannes
collection PubMed
description BACKGROUND: People with schizophrenia show a higher risk of committing violent offenses. Previous studies indicate that there are at least three subtypes of offenders with schizophrenia. OBJECTIVES: Employing latent class analysis, the goals of this study were to investigate the presence of homogeneous subgroups of offender patients in terms of remission in psychopathology during inpatient treatment and whether or not these are related to subtypes found in previous studies. Results should help identify patient subgroups benefitting insufficiently from forensic inpatient treatment and allow hypotheses on possibly more suitable therapy option for these patients. METHODS: A series of latent class analyses was used to explore extensive and detailed psychopathological reports of 370 offender patients with schizophrenia before and after inpatient treatment. RESULTS: A framework developed by Hodgins to identify subgroups of offenders suffering from schizophrenia is useful in predicting remission of psychopathology over psychiatric inpatient treatment. While “early starters” were most likely to experience remission of psychopathology over treatment, “late late starters” and a subgroup including patients from all three of Hodgins' subgroups in equal proportions benefited least. Negative symptoms generally seemed least likely to remit. CONCLUSION: Psychiatric treatment may have to be more tailored to offender patient subgroups to allow them to benefit more equally.
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spelling pubmed-81705742021-06-11 Individuals with schizophrenia who act violently towards others profit unequally from inpatient treatment—Identifying subgroups by latent class analysis Kirchebner, Johannes Lau, Steffen Kling, Sabine Sonnweber, Martina Günther, Moritz Philipp Int J Methods Psychiatr Res Original Article BACKGROUND: People with schizophrenia show a higher risk of committing violent offenses. Previous studies indicate that there are at least three subtypes of offenders with schizophrenia. OBJECTIVES: Employing latent class analysis, the goals of this study were to investigate the presence of homogeneous subgroups of offender patients in terms of remission in psychopathology during inpatient treatment and whether or not these are related to subtypes found in previous studies. Results should help identify patient subgroups benefitting insufficiently from forensic inpatient treatment and allow hypotheses on possibly more suitable therapy option for these patients. METHODS: A series of latent class analyses was used to explore extensive and detailed psychopathological reports of 370 offender patients with schizophrenia before and after inpatient treatment. RESULTS: A framework developed by Hodgins to identify subgroups of offenders suffering from schizophrenia is useful in predicting remission of psychopathology over psychiatric inpatient treatment. While “early starters” were most likely to experience remission of psychopathology over treatment, “late late starters” and a subgroup including patients from all three of Hodgins' subgroups in equal proportions benefited least. Negative symptoms generally seemed least likely to remit. CONCLUSION: Psychiatric treatment may have to be more tailored to offender patient subgroups to allow them to benefit more equally. John Wiley and Sons Inc. 2020-12-15 /pmc/articles/PMC8170574/ /pubmed/33320399 http://dx.doi.org/10.1002/mpr.1856 Text en © 2020 The Authors. International Journal of Methods in Psychiatric Research published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Article
Kirchebner, Johannes
Lau, Steffen
Kling, Sabine
Sonnweber, Martina
Günther, Moritz Philipp
Individuals with schizophrenia who act violently towards others profit unequally from inpatient treatment—Identifying subgroups by latent class analysis
title Individuals with schizophrenia who act violently towards others profit unequally from inpatient treatment—Identifying subgroups by latent class analysis
title_full Individuals with schizophrenia who act violently towards others profit unequally from inpatient treatment—Identifying subgroups by latent class analysis
title_fullStr Individuals with schizophrenia who act violently towards others profit unequally from inpatient treatment—Identifying subgroups by latent class analysis
title_full_unstemmed Individuals with schizophrenia who act violently towards others profit unequally from inpatient treatment—Identifying subgroups by latent class analysis
title_short Individuals with schizophrenia who act violently towards others profit unequally from inpatient treatment—Identifying subgroups by latent class analysis
title_sort individuals with schizophrenia who act violently towards others profit unequally from inpatient treatment—identifying subgroups by latent class analysis
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170574/
https://www.ncbi.nlm.nih.gov/pubmed/33320399
http://dx.doi.org/10.1002/mpr.1856
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