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Sex as an important factor in nanomedicine

Nanomedicine has demonstrated substantial potential to improve the quality and efficacy of healthcare systems. Although the promise of nanomedicine to transform conventional medicine is evident, significant numbers of therapeutic nanomedicine products have failed in clinical trials. Most studies in...

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Autores principales: Hajipour, Mohammah Javad, Aghaverdi, Haniyeh, Serpooshan, Vahid, Vali, Hojatollah, Sheibani, Sara, Mahmoudi, Morteza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170671/
https://www.ncbi.nlm.nih.gov/pubmed/34017011
http://dx.doi.org/10.1038/s41467-021-23230-9
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author Hajipour, Mohammah Javad
Aghaverdi, Haniyeh
Serpooshan, Vahid
Vali, Hojatollah
Sheibani, Sara
Mahmoudi, Morteza
author_facet Hajipour, Mohammah Javad
Aghaverdi, Haniyeh
Serpooshan, Vahid
Vali, Hojatollah
Sheibani, Sara
Mahmoudi, Morteza
author_sort Hajipour, Mohammah Javad
collection PubMed
description Nanomedicine has demonstrated substantial potential to improve the quality and efficacy of healthcare systems. Although the promise of nanomedicine to transform conventional medicine is evident, significant numbers of therapeutic nanomedicine products have failed in clinical trials. Most studies in nanomedicine have overlooked several important factors, including the significance of sex differences at various physiological levels. This report attempts to highlight the importance of sex in nanomedicine at cellular and molecular level. A more thorough consideration of sex physiology, among other critical variations (e.g., health status of individuals), would enable researchers to design and develop safer and more-efficient sex-specific diagnostic and therapeutic nanomedicine products.
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spelling pubmed-81706712021-06-07 Sex as an important factor in nanomedicine Hajipour, Mohammah Javad Aghaverdi, Haniyeh Serpooshan, Vahid Vali, Hojatollah Sheibani, Sara Mahmoudi, Morteza Nat Commun Review Article Nanomedicine has demonstrated substantial potential to improve the quality and efficacy of healthcare systems. Although the promise of nanomedicine to transform conventional medicine is evident, significant numbers of therapeutic nanomedicine products have failed in clinical trials. Most studies in nanomedicine have overlooked several important factors, including the significance of sex differences at various physiological levels. This report attempts to highlight the importance of sex in nanomedicine at cellular and molecular level. A more thorough consideration of sex physiology, among other critical variations (e.g., health status of individuals), would enable researchers to design and develop safer and more-efficient sex-specific diagnostic and therapeutic nanomedicine products. Nature Publishing Group UK 2021-05-20 /pmc/articles/PMC8170671/ /pubmed/34017011 http://dx.doi.org/10.1038/s41467-021-23230-9 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Review Article
Hajipour, Mohammah Javad
Aghaverdi, Haniyeh
Serpooshan, Vahid
Vali, Hojatollah
Sheibani, Sara
Mahmoudi, Morteza
Sex as an important factor in nanomedicine
title Sex as an important factor in nanomedicine
title_full Sex as an important factor in nanomedicine
title_fullStr Sex as an important factor in nanomedicine
title_full_unstemmed Sex as an important factor in nanomedicine
title_short Sex as an important factor in nanomedicine
title_sort sex as an important factor in nanomedicine
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170671/
https://www.ncbi.nlm.nih.gov/pubmed/34017011
http://dx.doi.org/10.1038/s41467-021-23230-9
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