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Sex as an important factor in nanomedicine
Nanomedicine has demonstrated substantial potential to improve the quality and efficacy of healthcare systems. Although the promise of nanomedicine to transform conventional medicine is evident, significant numbers of therapeutic nanomedicine products have failed in clinical trials. Most studies in...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170671/ https://www.ncbi.nlm.nih.gov/pubmed/34017011 http://dx.doi.org/10.1038/s41467-021-23230-9 |
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author | Hajipour, Mohammah Javad Aghaverdi, Haniyeh Serpooshan, Vahid Vali, Hojatollah Sheibani, Sara Mahmoudi, Morteza |
author_facet | Hajipour, Mohammah Javad Aghaverdi, Haniyeh Serpooshan, Vahid Vali, Hojatollah Sheibani, Sara Mahmoudi, Morteza |
author_sort | Hajipour, Mohammah Javad |
collection | PubMed |
description | Nanomedicine has demonstrated substantial potential to improve the quality and efficacy of healthcare systems. Although the promise of nanomedicine to transform conventional medicine is evident, significant numbers of therapeutic nanomedicine products have failed in clinical trials. Most studies in nanomedicine have overlooked several important factors, including the significance of sex differences at various physiological levels. This report attempts to highlight the importance of sex in nanomedicine at cellular and molecular level. A more thorough consideration of sex physiology, among other critical variations (e.g., health status of individuals), would enable researchers to design and develop safer and more-efficient sex-specific diagnostic and therapeutic nanomedicine products. |
format | Online Article Text |
id | pubmed-8170671 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-81706712021-06-07 Sex as an important factor in nanomedicine Hajipour, Mohammah Javad Aghaverdi, Haniyeh Serpooshan, Vahid Vali, Hojatollah Sheibani, Sara Mahmoudi, Morteza Nat Commun Review Article Nanomedicine has demonstrated substantial potential to improve the quality and efficacy of healthcare systems. Although the promise of nanomedicine to transform conventional medicine is evident, significant numbers of therapeutic nanomedicine products have failed in clinical trials. Most studies in nanomedicine have overlooked several important factors, including the significance of sex differences at various physiological levels. This report attempts to highlight the importance of sex in nanomedicine at cellular and molecular level. A more thorough consideration of sex physiology, among other critical variations (e.g., health status of individuals), would enable researchers to design and develop safer and more-efficient sex-specific diagnostic and therapeutic nanomedicine products. Nature Publishing Group UK 2021-05-20 /pmc/articles/PMC8170671/ /pubmed/34017011 http://dx.doi.org/10.1038/s41467-021-23230-9 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Review Article Hajipour, Mohammah Javad Aghaverdi, Haniyeh Serpooshan, Vahid Vali, Hojatollah Sheibani, Sara Mahmoudi, Morteza Sex as an important factor in nanomedicine |
title | Sex as an important factor in nanomedicine |
title_full | Sex as an important factor in nanomedicine |
title_fullStr | Sex as an important factor in nanomedicine |
title_full_unstemmed | Sex as an important factor in nanomedicine |
title_short | Sex as an important factor in nanomedicine |
title_sort | sex as an important factor in nanomedicine |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170671/ https://www.ncbi.nlm.nih.gov/pubmed/34017011 http://dx.doi.org/10.1038/s41467-021-23230-9 |
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