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The role of single-cell sequencing in studying tumour evolution

Tumour evolution is a complex interplay between the acquisition of somatic (epi)genomic changes in tumour cells and the phenotypic consequences they cause, all in the context of a changing microenvironment. Single-cell sequencing offers a window into this dynamic process at the ultimate resolution o...

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Detalles Bibliográficos
Autores principales: Mossner, Maximilian, Baker, Ann-Marie C, Graham, Trevor A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculty Opinions Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170688/
https://www.ncbi.nlm.nih.gov/pubmed/34131659
http://dx.doi.org/10.12703/r/10-49