AML-derived Extracellular Vesicles Confer De Novo Chemoresistance to Leukemic Myeloblast Cells by Promoting Drug Export Genes Expression and ROS Inhibition

In spite of successful initial remission, chemo-resistance and relapse are still concerning points in acute myeloid leukemia (AML) treatment strategies. Multidrug resistance (MDR) appears to be the major contributor of chemo-resistance, arising in some sub-clones of cancers and could be developed in...

Descripción completa

Detalles Bibliográficos
Autores principales: Barzegar, Mohieddin, Allahbakhshian Farsan, Mehdi, Amiri, Vahid, Mohammadi, Saeed, Shahsavan, Shaghayegh, Mirzaeian, Amin, Mohammadi, Mohammad Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170774/
https://www.ncbi.nlm.nih.gov/pubmed/34400967
http://dx.doi.org/10.22037/ijpr.2020.113272.14199

Ejemplares similares

Ejemplares similares