PS-341 alleviates chronic low-grade inflammation and improves insulin sensitivity through the inhibition of TM4 (UBAC2) degradation

BACKGROUND: The TM4 (UBAC2) protein, which contains 4 transmembrane domains and one ubiquitin binding domain, is mainly expressed in cell and nuclear membranes. The current research aimed to explore the role of TM4 in metabolic inflammation and to examine whether the ubiquitin–proteasome inhibitor P...

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Detalles Bibliográficos
Autores principales: Chen, Lili, Ye, Kuanping, Feng, Xiaocheng, Li, Lianxi, Li, Qin, Huang, Ying, Wang, Xuanchun, Li, Rumei, Hu, Cheng, Yang, Zhen, Lu, Bin, Yang, Yehong, Wen, Jie, Zhang, Zhaoyun, He, Min, Wang, Qinghua, Zhou, Wenbai, Li, Yintao, Liu, Naijia, Huang, Jinya, Shen, Qiwei, Yao, Qiyuan, Hu, Renming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170790/
https://www.ncbi.nlm.nih.gov/pubmed/34074311
http://dx.doi.org/10.1186/s12986-021-00579-8

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