Is the mechanism of COVID-19 coagulopathy still a rabbit’s hole?

The pathophysiology of COVID-19 is an enigma with its severity often determined by the extent of coagulopathy. Several regulatory pathways targeted by the SARS-CoV-2 include the renin-angiotensin system, von Willebrand Factor, and most importantly, the complement pathway. This article discusses thes...

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Autores principales: Rajan, Ashna, Thirunavukkarasu, Ganesh Keshav, Lockey, Richard F., Kolliputi, Narasaiah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
BITS and BYTES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170857/
https://www.ncbi.nlm.nih.gov/pubmed/34076828
http://dx.doi.org/10.1007/s12079-021-00613-7
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author Rajan, Ashna
Thirunavukkarasu, Ganesh Keshav
Lockey, Richard F.
Kolliputi, Narasaiah
author_facet Rajan, Ashna
Thirunavukkarasu, Ganesh Keshav
Lockey, Richard F.
Kolliputi, Narasaiah
author_sort Rajan, Ashna
collection PubMed
description The pathophysiology of COVID-19 is an enigma with its severity often determined by the extent of coagulopathy. Several regulatory pathways targeted by the SARS-CoV-2 include the renin-angiotensin system, von Willebrand Factor, and most importantly, the complement pathway. This article discusses these pathways to help design potential future therapies.
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spelling pubmed-81708572021-06-02 Is the mechanism of COVID-19 coagulopathy still a rabbit’s hole? Rajan, Ashna Thirunavukkarasu, Ganesh Keshav Lockey, Richard F. Kolliputi, Narasaiah J Cell Commun Signal BITS and BYTES The pathophysiology of COVID-19 is an enigma with its severity often determined by the extent of coagulopathy. Several regulatory pathways targeted by the SARS-CoV-2 include the renin-angiotensin system, von Willebrand Factor, and most importantly, the complement pathway. This article discusses these pathways to help design potential future therapies. Springer Netherlands 2021-06-02 2022-03 /pmc/articles/PMC8170857/ /pubmed/34076828 http://dx.doi.org/10.1007/s12079-021-00613-7 Text en © The International CCN Society 2021
spellingShingle BITS and BYTES
Rajan, Ashna
Thirunavukkarasu, Ganesh Keshav
Lockey, Richard F.
Kolliputi, Narasaiah
Is the mechanism of COVID-19 coagulopathy still a rabbit’s hole?
title Is the mechanism of COVID-19 coagulopathy still a rabbit’s hole?
title_full Is the mechanism of COVID-19 coagulopathy still a rabbit’s hole?
title_fullStr Is the mechanism of COVID-19 coagulopathy still a rabbit’s hole?
title_full_unstemmed Is the mechanism of COVID-19 coagulopathy still a rabbit’s hole?
title_short Is the mechanism of COVID-19 coagulopathy still a rabbit’s hole?
title_sort is the mechanism of covid-19 coagulopathy still a rabbit’s hole?
topic BITS and BYTES
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170857/
https://www.ncbi.nlm.nih.gov/pubmed/34076828
http://dx.doi.org/10.1007/s12079-021-00613-7
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