The emerging osteo-metabolic phenotype of COVID-19: clinical and pathophysiological aspects

An emerging feature of COVID-19 is a clinically relevant osteo-metabolic phenotype characterized by widespread acute hypocalcaemia and chronic hypovitaminosis D with high prevalence of vertebral fractures. This phenotype might have negative effects on disease severity and its components could repres...

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Autores principales: di Filippo, Luigi, Frara, Stefano, Giustina, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170860/
https://www.ncbi.nlm.nih.gov/pubmed/34079100
http://dx.doi.org/10.1038/s41574-021-00516-y
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author di Filippo, Luigi
Frara, Stefano
Giustina, Andrea
author_facet di Filippo, Luigi
Frara, Stefano
Giustina, Andrea
author_sort di Filippo, Luigi
collection PubMed
description An emerging feature of COVID-19 is a clinically relevant osteo-metabolic phenotype characterized by widespread acute hypocalcaemia and chronic hypovitaminosis D with high prevalence of vertebral fractures. This phenotype might have negative effects on disease severity and its components could represent possible targets for prevention of SARS-CoV-2 infection and poor COVID-19 outcomes.
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spelling pubmed-81708602021-06-02 The emerging osteo-metabolic phenotype of COVID-19: clinical and pathophysiological aspects di Filippo, Luigi Frara, Stefano Giustina, Andrea Nat Rev Endocrinol Comment An emerging feature of COVID-19 is a clinically relevant osteo-metabolic phenotype characterized by widespread acute hypocalcaemia and chronic hypovitaminosis D with high prevalence of vertebral fractures. This phenotype might have negative effects on disease severity and its components could represent possible targets for prevention of SARS-CoV-2 infection and poor COVID-19 outcomes. Nature Publishing Group UK 2021-06-02 2021 /pmc/articles/PMC8170860/ /pubmed/34079100 http://dx.doi.org/10.1038/s41574-021-00516-y Text en © Springer Nature Limited 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Comment
di Filippo, Luigi
Frara, Stefano
Giustina, Andrea
The emerging osteo-metabolic phenotype of COVID-19: clinical and pathophysiological aspects
title The emerging osteo-metabolic phenotype of COVID-19: clinical and pathophysiological aspects
title_full The emerging osteo-metabolic phenotype of COVID-19: clinical and pathophysiological aspects
title_fullStr The emerging osteo-metabolic phenotype of COVID-19: clinical and pathophysiological aspects
title_full_unstemmed The emerging osteo-metabolic phenotype of COVID-19: clinical and pathophysiological aspects
title_short The emerging osteo-metabolic phenotype of COVID-19: clinical and pathophysiological aspects
title_sort emerging osteo-metabolic phenotype of covid-19: clinical and pathophysiological aspects
topic Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170860/
https://www.ncbi.nlm.nih.gov/pubmed/34079100
http://dx.doi.org/10.1038/s41574-021-00516-y
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