Parkinson mice show functional and molecular changes in the gut long before motoric disease onset

BACKGROUND: There is increasing evidence that Parkinson’s disease (PD) might start in the gut, thus involving and compromising also the enteric nervous system (ENS). At the clinical onset of the disease the majority of dopaminergic neurons in the midbrain is already destroyed, so that the lack of ea...

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Detalles Bibliográficos
Autores principales: Gries, Manuela, Christmann, Anne, Schulte, Steven, Weyland, Maximilian, Rommel, Stephanie, Martin, Monika, Baller, Marko, Röth, Ralph, Schmitteckert, Stefanie, Unger, Marcus, Liu, Yang, Sommer, Frederik, Mühlhaus, Timo, Schroda, Michael, Timmermans, Jean-Pierre, Pintelon, Isabel, Rappold, Gudrun A., Britschgi, Markus, Lashuel, Hilal, Menger, Michael D., Laschke, Matthias W., Niesler, Beate, Schäfer, Karl-Herbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170976/
https://www.ncbi.nlm.nih.gov/pubmed/34078425
http://dx.doi.org/10.1186/s13024-021-00439-2

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