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Effects of WNT1 c.110 T>C and c.505G>T mutations on osteoblast differentiation via the WNT1/β-catenin signaling pathway

BACKGROUND: WNT1 c.110 T>C and c.505G>T missense mutations have been identified in patients with osteogenesis imperfecta (OI). Whether these mutations affect osteoblast differentiation remains to be determined. This study aimed to investigate the effects of WNT1 c.110 T>C and c.505G>T mu...

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Detalles Bibliográficos
Autores principales:	Zhang, Bashan, Li, Rong, Wang, Wenfeng, Zhou, Xueming, Luo, Beijing, Zhu, Zinian, Zhang, Xibo, Ding, Aijiao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170984/ https://www.ncbi.nlm.nih.gov/pubmed/34078411 http://dx.doi.org/10.1186/s13018-021-02495-2

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