Cargando…

Mendelian randomization studies of brain MRI yield insights into the pathogenesis of neuropsychiatric disorders

BACKGROUND: Observational studies have identified various associations between neuroimaging alterations and neuropsychiatric disorders. However, whether such associations could truly reflect causal relations remains still unknown. RESULTS: Here, we leveraged genome-wide association studies (GWAS) su...

Descripción completa

Detalles Bibliográficos
Autores principales:	Song, Weichen, Qian, Wei, Wang, Weidi, Yu, Shunying, Lin, Guan Ning
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8171058/ https://www.ncbi.nlm.nih.gov/pubmed/34078268 http://dx.doi.org/10.1186/s12864-021-07661-8

Ejemplares similares

A Comprehensive Evaluation of Cross-Omics Blood-Based Biomarkers for Neuropsychiatric Disorders
por: Song, Weichen, et al.
Publicado: (2021)

Dissection of the Genetic Association between Anorexia Nervosa and Obsessive–Compulsive Disorder at the Network and Cellular Levels
por: Song, Weichen, et al.
Publicado: (2021)

Mendelian Randomization and GWAS Meta Analysis Revealed the Risk-Increasing Effect of Schizophrenia on Cancers
por: Yuan, Kai, et al.
Publicado: (2022)

Genome-wide and Mendelian randomisation studies of liver MRI yield insights into the pathogenesis of steatohepatitis
por: Parisinos, Constantinos A., et al.
Publicado: (2020)

Inflammation and Brain Structure in Schizophrenia and Other Neuropsychiatric Disorders: A Mendelian Randomization Study
por: Williams, John A., et al.
Publicado: (2022)

PsyMuKB: An Integrative De Novo Variant Knowledge Base for Developmental Disorders
por: Lin, Guan Ning, et al.
Publicado: (2019)

Spatiotemporal 7q11.23 protein network analysis implicates the role of DNA repair pathway during human brain development
por: Chen, Liang, et al.
Publicado: (2021)

Corrigendum to: “Genome-wide and Mendelian randomisation studies of liver MRI yield insights into the pathogenesis of steatohepatitis” [J Hepatol (2020) 241-251]
por: Parisinos, Constantinos A., et al.
Publicado: (2020)

New insights into the pathogenesis and prevention of tuberous sclerosis-associated neuropsychiatric disorders (TAND)
por: Gipson, Tanjala T., et al.
Publicado: (2017)

Synaptic Wiring of Corticostriatal Circuits in Basal Ganglia: Insights into the Pathogenesis of Neuropsychiatric Disorders
por: Kuo, Hsiao-Ying, et al.
Publicado: (2019)

Appraising the causal relationship between plasma caffeine levels and neuropsychiatric disorders through Mendelian randomization
por: Woolf, Benjamin, et al.
Publicado: (2023)

Association of Cortisol Levels With Neuropsychiatric Functions: A Mendelian Randomization Analysis
por: Zhou, Xiang, et al.
Publicado: (2019)

Transcriptome-wide association analysis of brain structures yields insights into pleiotropy with complex neuropsychiatric traits
por: Zhao, Bingxin, et al.
Publicado: (2021)

Assessment of Bidirectional Relationships between Leisure Sedentary Behaviors and Neuropsychiatric Disorders: A Two-Sample Mendelian Randomization Study
por: He, Qian, et al.
Publicado: (2022)

Genome-wide association study and Mendelian randomization analysis provide insights for improving rice yield potential
por: Su, Jing, et al.
Publicado: (2021)

Yield of brain MRI in children with autism spectrum disorder
por: Byrne, D, et al.
Publicado: (2023)

Risk of Neuropsychiatric Adverse Effects of Lipid-Lowering Drugs: A Mendelian Randomization Study
por: Alghamdi, Jahad, et al.
Publicado: (2018)

A Comprehensive Study of De Novo Mutations on the Protein-Protein Interaction Interfaces Provides New Insights into Developmental Delay
por: Maharjan, Dhruba Tara, et al.
Publicado: (2022)

De novo mutations identified by whole-genome sequencing implicate chromatin modifications in obsessive-compulsive disorder
por: Lin, Guan Ning, et al.
Publicado: (2022)

Integrative enrichment analysis of gene expression based on an artificial neuron
por: Jiang, Xue, et al.
Publicado: (2021)

Proteostasis and RNA Binding Proteins in Synaptic Plasticity and in the Pathogenesis of Neuropsychiatric Disorders
por: Klein, Matthew E., et al.
Publicado: (2016)

Editorial: Neuroimaging insights into the link between sleep disturbances and neuropsychiatric disorders
por: von Deneen, Karen M., et al.
Publicado: (2023)

Circulating S100B levels at birth and risk of six major neuropsychiatric or neurological disorders: a two-sample Mendelian Randomization Study
por: Pan, Mengyu, et al.
Publicado: (2023)

Progress in the Pathogenesis and Treatment of Neuropsychiatric Systemic Lupus Erythematosus
por: Wang, Minhui, et al.
Publicado: (2022)

Role of Hybrid Brain Imaging in Neuropsychiatric Disorders
por: Burhan, Amer M., et al.
Publicado: (2015)

Mendelian Randomization Analysis Provides Insights into the Pathogenesis of Serum Levels of Branched-Chain Amino Acids in Cardiovascular Disease
por: Jiang, Wenxi, et al.
Publicado: (2023)

Does COVID-19 increase the risk of neuropsychiatric sequelae? Evidence from a mendelian randomization approach
por: Tirozzi, Alfonsina, et al.
Publicado: (2022)

Alternatively Splicing Interactomes Identify Novel Isoform-Specific Partners for NSD2
por: Wang, Weidi, et al.
Publicado: (2021)

Morphostructural MRI Abnormalities Related to Neuropsychiatric Disorders Associated to Multiple Sclerosis
por: Bonavita, Simona, et al.
Publicado: (2013)

Activin Signaling in the Pathogenesis and Therapy of Neuropsychiatric Diseases
por: Link, Andrea S., et al.
Publicado: (2016)

Genetic Insights into Obesity and Brain: Combine Mendelian Randomization Study and Gene Expression Analysis
por: Chen, Leian, et al.
Publicado: (2023)

A comparison framework and guideline of clustering methods for mass cytometry data
por: Liu, Xiao, et al.
Publicado: (2019)

Stepwise use of genomics and transcriptomics technologies increases diagnostic yield in Mendelian disorders
por: Colin, Estelle, et al.
Publicado: (2023)

Noteworthy perspectives on microglia in neuropsychiatric disorders
por: Zhu, Hongrui, et al.
Publicado: (2023)

Brain CB(2) Receptors: Implications for Neuropsychiatric Disorders
por: Roche, Michelle, et al.
Publicado: (2010)

mTOR-Related Brain Dysfunctions in Neuropsychiatric Disorders
por: Ryskalin, Larisa, et al.
Publicado: (2018)

Neuropsychiatric Disorders: Influence of Gut Microbe to Brain Signalling
por: Scriven, Mary, et al.
Publicado: (2018)

Editorial: Emotional Disturbance and Brain Imaging in Neuropsychiatric Disorders
por: Esposito, Roberto, et al.
Publicado: (2021)

The role of the microbiota-gut-brain axis in neuropsychiatric disorders
por: Generoso, Jaqueline S., et al.
Publicado: (2020)

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure
por: Shah, Sonia, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_ltcac56hblfrao4cgmtlfe21hh