A nano-predator of pathological MDMX construct by clearable supramolecular gold(I)-thiol-peptide complexes achieves safe and potent anti-tumor activity

As alternatives to small-molecular proteolysis-targeting chimeras (PROTAC), peptide-based molecular glues (MG) are a broad range of dual-functional ligands that simultaneously bind with targetable proteins and E3 ligases by mimicking proteinprotein interaction (PPI) partners. Methods: Herein, we des...

Descripción completa

Detalles Bibliográficos
Autores principales: Yan, Siqi, Yan, Jin, Liu, Dan, Li, Xiang, Kang, Qianyan, You, Weiming, Zhang, Jinghua, Wang, Lei, Tian, Zhiqi, Lu, Wuyuan, Liu, Wenjia, He, Wangxiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8171083/
https://www.ncbi.nlm.nih.gov/pubmed/34093856
http://dx.doi.org/10.7150/thno.59020

Ejemplares similares

Ejemplares similares