Intratumoral expression of interleukin 23 variants using oncolytic vaccinia virus elicit potent antitumor effects on multiple tumor models via tumor microenvironment modulation

Background: Newly emerging cancer immunotherapy has led to significant progress in cancer treatment; however, its efficacy is limited in solid tumors since the majority of them are “cold” tumors. Oncolytic viruses, especially when properly armed, can directly target tumor cells and indirectly modula...

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Detalles Bibliográficos
Autores principales: Chen, Lingjuan, Chen, Hongqi, Ye, Junjie, Ge, Yan, Wang, Haiyan, Dai, Enyong, Ren, Jinghua, Liu, Weilin, Ma, Congrong, Ju, Songguang, Guo, Z. Sheng, Liu, Zuqiang, Bartlett, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8171085/
https://www.ncbi.nlm.nih.gov/pubmed/34093846
http://dx.doi.org/10.7150/thno.56494

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