Nanoparticle encapsulation of non-genotoxic p53 activator Inauhzin-C for improved therapeutic efficacy

The tumor suppressor protein p53 remains in a wild type but inactive form in ~50% of all human cancers. Thus, activating it becomes an attractive approach for targeted cancer therapies. In this regard, our lab has previously discovered a small molecule, Inauhzin (INZ), as a potent p53 activator with...

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Detalles Bibliográficos
Autores principales: Bhattarai, Nimisha, Wang, Jieqiong, Nguyen, Daniel, Yang, Xiaoxiao, Helmers, Linh, Paruch, Jennifer, Li, Li, Zhang, Yiwei, Meng, Kun, Wang, Alun, Jayawickramarajah, Janarthanan, Wang, Binghe, Zeng, Shelya, Lu, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8171090/
https://www.ncbi.nlm.nih.gov/pubmed/34093867
http://dx.doi.org/10.7150/thno.57404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8171090/
https://www.ncbi.nlm.nih.gov/pubmed/34093867
http://dx.doi.org/10.7150/thno.57404

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