Cancer-derived exosomal miR-138-5p modulates polarization of tumor-associated macrophages through inhibition of KDM6B

Rationale: Differential activation of macrophages correlates closely with tumor progression, and the epigenetic factor lysine demethylase 6B (KDM6B, previously named JMJD3) mediates the regulation of macrophage polarization through an unknown mechanism. Methods: We developed a suspension coculture s...

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Detalles Bibliográficos
Autores principales: Xun, Jing, Du, Lingfang, Gao, Ruifang, Shen, Long, Wang, Dekun, Kang, Lichun, Chen, Chuan'ai, Zhang, Zhujun, Zhang, Yuying, Yue, Shijing, Feng, Shuxin, Xiang, Rong, Mi, Xue, Tan, Xiaoyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8171095/
https://www.ncbi.nlm.nih.gov/pubmed/34093857
http://dx.doi.org/10.7150/thno.51864

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