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A case of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) presenting as post-infectious manifestation of SARS-CoV-2 infection

White matter hyperintensities (WMHs) lacunar infarcts and cerebral microbleeds are well-established features associated with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). Increasing case reports and series recounts a wide array of neurological...

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Autores principales: Rajendran, Ishwariya, Natarajan, Madhu Dutta, Narwani, Pooja, Alzouabi, Omran, Kawafi, Khalil, Khanna, Navin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Institute of Radiology. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8171128/
https://www.ncbi.nlm.nih.gov/pubmed/34131509
http://dx.doi.org/10.1259/bjrcr.20210020
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author Rajendran, Ishwariya
Natarajan, Madhu Dutta
Narwani, Pooja
Alzouabi, Omran
Kawafi, Khalil
Khanna, Navin
author_facet Rajendran, Ishwariya
Natarajan, Madhu Dutta
Narwani, Pooja
Alzouabi, Omran
Kawafi, Khalil
Khanna, Navin
author_sort Rajendran, Ishwariya
collection PubMed
description White matter hyperintensities (WMHs) lacunar infarcts and cerebral microbleeds are well-established features associated with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). Increasing case reports and series recounts a wide array of neurological manifestations of COVID-19 including acute cerebrovascular disease, encephalopathy, encephalitis and demyelination. Recently association between COVID-19 and CADASIL has been identified. We describe an unusual case of CADASIL diagnosed as a possible post-infectious manifestation of COVID-19 patient with imaging features closely resembling post-infectious encephalomyelitis.
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spelling pubmed-81711282021-06-14 A case of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) presenting as post-infectious manifestation of SARS-CoV-2 infection Rajendran, Ishwariya Natarajan, Madhu Dutta Narwani, Pooja Alzouabi, Omran Kawafi, Khalil Khanna, Navin BJR Case Rep Case Report White matter hyperintensities (WMHs) lacunar infarcts and cerebral microbleeds are well-established features associated with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). Increasing case reports and series recounts a wide array of neurological manifestations of COVID-19 including acute cerebrovascular disease, encephalopathy, encephalitis and demyelination. Recently association between COVID-19 and CADASIL has been identified. We describe an unusual case of CADASIL diagnosed as a possible post-infectious manifestation of COVID-19 patient with imaging features closely resembling post-infectious encephalomyelitis. The British Institute of Radiology. 2021-04-09 /pmc/articles/PMC8171128/ /pubmed/34131509 http://dx.doi.org/10.1259/bjrcr.20210020 Text en © 2021 The Authors. Published by the British Institute of Radiology https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
spellingShingle Case Report
Rajendran, Ishwariya
Natarajan, Madhu Dutta
Narwani, Pooja
Alzouabi, Omran
Kawafi, Khalil
Khanna, Navin
A case of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) presenting as post-infectious manifestation of SARS-CoV-2 infection
title A case of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) presenting as post-infectious manifestation of SARS-CoV-2 infection
title_full A case of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) presenting as post-infectious manifestation of SARS-CoV-2 infection
title_fullStr A case of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) presenting as post-infectious manifestation of SARS-CoV-2 infection
title_full_unstemmed A case of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) presenting as post-infectious manifestation of SARS-CoV-2 infection
title_short A case of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) presenting as post-infectious manifestation of SARS-CoV-2 infection
title_sort case of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (cadasil) presenting as post-infectious manifestation of sars-cov-2 infection
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8171128/
https://www.ncbi.nlm.nih.gov/pubmed/34131509
http://dx.doi.org/10.1259/bjrcr.20210020
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