Acute Myeloid Leukemia Complicated by Hyperleukocytosis and Leukostasis in the Emergency Department

Acute myeloid leukemia (AML) and other hematologic malignancies can be complicated by hyperleukocytosis, which leads to an increased risk for other severe complications such as tumor lysis syndrome, disseminated intravascular coagulation (DIC), and leukostasis. In this report, we present a case of a...

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Detalles Bibliográficos
Autores principales: Ngo, Ryan T, Webb McAdams, Amanda L, Furiato, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Emergency Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8171272/
https://www.ncbi.nlm.nih.gov/pubmed/34094792
http://dx.doi.org/10.7759/cureus.15392
Descripción
Sumario:Acute myeloid leukemia (AML) and other hematologic malignancies can be complicated by hyperleukocytosis, which leads to an increased risk for other severe complications such as tumor lysis syndrome, disseminated intravascular coagulation (DIC), and leukostasis. In this report, we present a case of a 65-year-old female with newly diagnosed AML complicated by leukostasis. We briefly review the clinical significance as well as initial diagnostic and therapeutic considerations pertaining to hyperleukocytosis and its associated complications.

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