Acute Myeloid Leukemia Complicated by Hyperleukocytosis and Leukostasis in the Emergency Department

Acute myeloid leukemia (AML) and other hematologic malignancies can be complicated by hyperleukocytosis, which leads to an increased risk for other severe complications such as tumor lysis syndrome, disseminated intravascular coagulation (DIC), and leukostasis. In this report, we present a case of a...

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Detalles Bibliográficos
Autores principales: Ngo, Ryan T, Webb McAdams, Amanda L, Furiato, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Emergency Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8171272/
https://www.ncbi.nlm.nih.gov/pubmed/34094792
http://dx.doi.org/10.7759/cureus.15392
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author Ngo, Ryan T
Webb McAdams, Amanda L
Furiato, Anthony
author_facet Ngo, Ryan T
Webb McAdams, Amanda L
Furiato, Anthony
author_sort Ngo, Ryan T
collection PubMed
description Acute myeloid leukemia (AML) and other hematologic malignancies can be complicated by hyperleukocytosis, which leads to an increased risk for other severe complications such as tumor lysis syndrome, disseminated intravascular coagulation (DIC), and leukostasis. In this report, we present a case of a 65-year-old female with newly diagnosed AML complicated by leukostasis. We briefly review the clinical significance as well as initial diagnostic and therapeutic considerations pertaining to hyperleukocytosis and its associated complications.
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spelling pubmed-81712722021-06-04 Acute Myeloid Leukemia Complicated by Hyperleukocytosis and Leukostasis in the Emergency Department Ngo, Ryan T Webb McAdams, Amanda L Furiato, Anthony Cureus Emergency Medicine Acute myeloid leukemia (AML) and other hematologic malignancies can be complicated by hyperleukocytosis, which leads to an increased risk for other severe complications such as tumor lysis syndrome, disseminated intravascular coagulation (DIC), and leukostasis. In this report, we present a case of a 65-year-old female with newly diagnosed AML complicated by leukostasis. We briefly review the clinical significance as well as initial diagnostic and therapeutic considerations pertaining to hyperleukocytosis and its associated complications. Cureus 2021-06-02 /pmc/articles/PMC8171272/ /pubmed/34094792 http://dx.doi.org/10.7759/cureus.15392 Text en Copyright © 2021, Ngo et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Emergency Medicine
Ngo, Ryan T
Webb McAdams, Amanda L
Furiato, Anthony
Acute Myeloid Leukemia Complicated by Hyperleukocytosis and Leukostasis in the Emergency Department
title Acute Myeloid Leukemia Complicated by Hyperleukocytosis and Leukostasis in the Emergency Department
title_full Acute Myeloid Leukemia Complicated by Hyperleukocytosis and Leukostasis in the Emergency Department
title_fullStr Acute Myeloid Leukemia Complicated by Hyperleukocytosis and Leukostasis in the Emergency Department
title_full_unstemmed Acute Myeloid Leukemia Complicated by Hyperleukocytosis and Leukostasis in the Emergency Department
title_short Acute Myeloid Leukemia Complicated by Hyperleukocytosis and Leukostasis in the Emergency Department
title_sort acute myeloid leukemia complicated by hyperleukocytosis and leukostasis in the emergency department
topic Emergency Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8171272/
https://www.ncbi.nlm.nih.gov/pubmed/34094792
http://dx.doi.org/10.7759/cureus.15392
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