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Synthesis of 1,3-disubstituted bicyclo[1.1.0]butanes via directed bridgehead functionalization

Bicyclo[1.1.0]butanes (BCBs) are increasingly valued as intermediates in ‘strain release’ chemistry for the synthesis of substituted four membered rings and bicyclo[1.1.1]pentanes, with applications including bioconjugation processes. Variation of the BCB bridgehead substituents can be challenging d...

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Detalles Bibliográficos
Autores principales:	McNamee, Ryan E., Haugland, Marius M., Nugent, Jeremy, Chan, Rachel, Christensen, Kirsten E., Anderson, Edward A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2021
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8171340/ https://www.ncbi.nlm.nih.gov/pubmed/34163838 http://dx.doi.org/10.1039/d1sc01836a

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