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Type I Gastric Neuroendocrine Tumor Presenting as Acute Upper Gastrointestinal Bleed
Gastric neuroendocrine tumors (GNETs) are rare and subdivided into type I, type II, and type III. Types I and II are gastrin-dependent and are usually benign, whereas type III is gastrin-independent and more aggressive. Type I accounts for 70-80% of all GNETs. Most of them are asymptomatic and incid...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172005/ https://www.ncbi.nlm.nih.gov/pubmed/34094786 http://dx.doi.org/10.7759/cureus.15343 |
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author | Bapatla, Anusha Syed, Ameena Mohammed, Abu Fazal Shaik Jones, Cortney V Ismail, Rana |
author_facet | Bapatla, Anusha Syed, Ameena Mohammed, Abu Fazal Shaik Jones, Cortney V Ismail, Rana |
author_sort | Bapatla, Anusha |
collection | PubMed |
description | Gastric neuroendocrine tumors (GNETs) are rare and subdivided into type I, type II, and type III. Types I and II are gastrin-dependent and are usually benign, whereas type III is gastrin-independent and more aggressive. Type I accounts for 70-80% of all GNETs. Most of them are asymptomatic and incidentally detected on endoscopy. It can sometimes present with iron and B12 deficiency, dyspepsia, and less commonly with an upper GI bleed. We present a case of type I GNET who came to the hospital with melena and esophagogastroduodenoscopy (EGD) showing a 3-cm bleeding polyp and histopathology revealing a well-differentiated neuroendocrine tumor with angioinvasion. |
format | Online Article Text |
id | pubmed-8172005 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-81720052021-06-04 Type I Gastric Neuroendocrine Tumor Presenting as Acute Upper Gastrointestinal Bleed Bapatla, Anusha Syed, Ameena Mohammed, Abu Fazal Shaik Jones, Cortney V Ismail, Rana Cureus Endocrinology/Diabetes/Metabolism Gastric neuroendocrine tumors (GNETs) are rare and subdivided into type I, type II, and type III. Types I and II are gastrin-dependent and are usually benign, whereas type III is gastrin-independent and more aggressive. Type I accounts for 70-80% of all GNETs. Most of them are asymptomatic and incidentally detected on endoscopy. It can sometimes present with iron and B12 deficiency, dyspepsia, and less commonly with an upper GI bleed. We present a case of type I GNET who came to the hospital with melena and esophagogastroduodenoscopy (EGD) showing a 3-cm bleeding polyp and histopathology revealing a well-differentiated neuroendocrine tumor with angioinvasion. Cureus 2021-05-31 /pmc/articles/PMC8172005/ /pubmed/34094786 http://dx.doi.org/10.7759/cureus.15343 Text en Copyright © 2021, Bapatla et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Endocrinology/Diabetes/Metabolism Bapatla, Anusha Syed, Ameena Mohammed, Abu Fazal Shaik Jones, Cortney V Ismail, Rana Type I Gastric Neuroendocrine Tumor Presenting as Acute Upper Gastrointestinal Bleed |
title | Type I Gastric Neuroendocrine Tumor Presenting as Acute Upper Gastrointestinal Bleed |
title_full | Type I Gastric Neuroendocrine Tumor Presenting as Acute Upper Gastrointestinal Bleed |
title_fullStr | Type I Gastric Neuroendocrine Tumor Presenting as Acute Upper Gastrointestinal Bleed |
title_full_unstemmed | Type I Gastric Neuroendocrine Tumor Presenting as Acute Upper Gastrointestinal Bleed |
title_short | Type I Gastric Neuroendocrine Tumor Presenting as Acute Upper Gastrointestinal Bleed |
title_sort | type i gastric neuroendocrine tumor presenting as acute upper gastrointestinal bleed |
topic | Endocrinology/Diabetes/Metabolism |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172005/ https://www.ncbi.nlm.nih.gov/pubmed/34094786 http://dx.doi.org/10.7759/cureus.15343 |
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