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Type I Gastric Neuroendocrine Tumor Presenting as Acute Upper Gastrointestinal Bleed

Gastric neuroendocrine tumors (GNETs) are rare and subdivided into type I, type II, and type III. Types I and II are gastrin-dependent and are usually benign, whereas type III is gastrin-independent and more aggressive. Type I accounts for 70-80% of all GNETs. Most of them are asymptomatic and incid...

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Autores principales: Bapatla, Anusha, Syed, Ameena, Mohammed, Abu Fazal Shaik, Jones, Cortney V, Ismail, Rana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172005/
https://www.ncbi.nlm.nih.gov/pubmed/34094786
http://dx.doi.org/10.7759/cureus.15343
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author Bapatla, Anusha
Syed, Ameena
Mohammed, Abu Fazal Shaik
Jones, Cortney V
Ismail, Rana
author_facet Bapatla, Anusha
Syed, Ameena
Mohammed, Abu Fazal Shaik
Jones, Cortney V
Ismail, Rana
author_sort Bapatla, Anusha
collection PubMed
description Gastric neuroendocrine tumors (GNETs) are rare and subdivided into type I, type II, and type III. Types I and II are gastrin-dependent and are usually benign, whereas type III is gastrin-independent and more aggressive. Type I accounts for 70-80% of all GNETs. Most of them are asymptomatic and incidentally detected on endoscopy. It can sometimes present with iron and B12 deficiency, dyspepsia, and less commonly with an upper GI bleed. We present a case of type I GNET who came to the hospital with melena and esophagogastroduodenoscopy (EGD) showing a 3-cm bleeding polyp and histopathology revealing a well-differentiated neuroendocrine tumor with angioinvasion.
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spelling pubmed-81720052021-06-04 Type I Gastric Neuroendocrine Tumor Presenting as Acute Upper Gastrointestinal Bleed Bapatla, Anusha Syed, Ameena Mohammed, Abu Fazal Shaik Jones, Cortney V Ismail, Rana Cureus Endocrinology/Diabetes/Metabolism Gastric neuroendocrine tumors (GNETs) are rare and subdivided into type I, type II, and type III. Types I and II are gastrin-dependent and are usually benign, whereas type III is gastrin-independent and more aggressive. Type I accounts for 70-80% of all GNETs. Most of them are asymptomatic and incidentally detected on endoscopy. It can sometimes present with iron and B12 deficiency, dyspepsia, and less commonly with an upper GI bleed. We present a case of type I GNET who came to the hospital with melena and esophagogastroduodenoscopy (EGD) showing a 3-cm bleeding polyp and histopathology revealing a well-differentiated neuroendocrine tumor with angioinvasion. Cureus 2021-05-31 /pmc/articles/PMC8172005/ /pubmed/34094786 http://dx.doi.org/10.7759/cureus.15343 Text en Copyright © 2021, Bapatla et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Endocrinology/Diabetes/Metabolism
Bapatla, Anusha
Syed, Ameena
Mohammed, Abu Fazal Shaik
Jones, Cortney V
Ismail, Rana
Type I Gastric Neuroendocrine Tumor Presenting as Acute Upper Gastrointestinal Bleed
title Type I Gastric Neuroendocrine Tumor Presenting as Acute Upper Gastrointestinal Bleed
title_full Type I Gastric Neuroendocrine Tumor Presenting as Acute Upper Gastrointestinal Bleed
title_fullStr Type I Gastric Neuroendocrine Tumor Presenting as Acute Upper Gastrointestinal Bleed
title_full_unstemmed Type I Gastric Neuroendocrine Tumor Presenting as Acute Upper Gastrointestinal Bleed
title_short Type I Gastric Neuroendocrine Tumor Presenting as Acute Upper Gastrointestinal Bleed
title_sort type i gastric neuroendocrine tumor presenting as acute upper gastrointestinal bleed
topic Endocrinology/Diabetes/Metabolism
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172005/
https://www.ncbi.nlm.nih.gov/pubmed/34094786
http://dx.doi.org/10.7759/cureus.15343
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