A novel method of screening combinations of angiostatics identifies bevacizumab and temsirolimus as synergistic inhibitors of glioma-induced angiogenesis

Tumor angiogenesis is critical for the growth and progression of cancer. As such, angiostasis is a treatment modality for cancer with potential utility for multiple types of cancer and fewer side effects. However, clinical success of angiostatic monotherapies has been moderate, at best, causing angi...

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Detalles Bibliográficos
Autores principales: Dorrell, Michael I., Kast-Woelbern, Heidi R., Botts, Ryan T., Bravo, Stephen A., Tremblay, Jacob R., Giles, Sarah, Wada, Jessica F., Alexander, MaryAnn, Garcia, Eric, Villegas, Gabriel, Booth, Caylor B., Purington, Kaitlyn J., Everett, Haylie M., Siles, Erik N., Wheelock, Michael, Silva, Jordan A., Fortin, Bridget M., Lowey, Connor A., Hale, Allison L., Kurz, Troy L., Rusing, Jack C., Goral, Dawn M., Thompson, Paul, Johnson, Alec M., Elson, Daniel J., Tadros, Roujih, Gillette, Charisa E., Coopwood, Carley, Rausch, Amy L., Snowbarger, Jeffrey M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172048/
https://www.ncbi.nlm.nih.gov/pubmed/34077449
http://dx.doi.org/10.1371/journal.pone.0252233

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