The extracellular matrix protein agrin is essential for epicardial epithelial-to-mesenchymal transition during heart development

During heart development, epicardial cells residing within the outer layer undergo epithelial-mesenchymal transition (EMT) and migrate into the underlying myocardium to support organ growth and morphogenesis. Disruption of epicardial EMT results in embryonic lethality, yet its regulation is poorly u...

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Detalles Bibliográficos
Autores principales: Sun, Xin, Malandraki-Miller, Sophia, Kennedy, Tahnee, Bassat, Elad, Klaourakis, Konstantinos, Zhao, Jia, Gamen, Elisabetta, Vieira, Joaquim Miguel, Tzahor, Eldad, Riley, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172119/
https://www.ncbi.nlm.nih.gov/pubmed/33969874
http://dx.doi.org/10.1242/dev.197525

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