Prdm16-mediated H3K9 methylation controls fibro-adipogenic progenitors identity during skeletal muscle repair

H3K9 methylation maintains cell identity orchestrating stable silencing and anchoring of alternate fate genes within the heterochromatic compartment underneath the nuclear lamina (NL). However, how cell type–specific genomic regions are specifically targeted to the NL is still elusive. Using fibro-a...

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Detalles Bibliográficos
Autores principales: Biferali, Beatrice, Bianconi, Valeria, Perez, Daniel Fernandez, Kronawitter, Sophie Pöhle, Marullo, Fabrizia, Maggio, Roberta, Santini, Tiziana, Polverino, Federica, Biagioni, Stefano, Summa, Vincenzo, Toniatti, Carlo, Pasini, Diego, Stricker, Sigmar, Di Fabio, Romano, Chiacchiera, Fulvio, Peruzzi, Giovanna, Mozzetta, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172132/
https://www.ncbi.nlm.nih.gov/pubmed/34078594
http://dx.doi.org/10.1126/sciadv.abd9371

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