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ALOX5AP Predicts Poor Prognosis by Enhancing M2 Macrophages Polarization and Immunosuppression in Serous Ovarian Cancer Microenvironment

BACKGROUND: Serous ovarian cancer (SOC) is a highly lethal gynecological malignancy with poor prognosis. Given the importance of the immune-related tumor microenvironment (TME) in ovarian cancer, investigating tumor-immune interactions and identifying novel prognostic and therapeutic targets in SOC...

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Detalles Bibliográficos
Autores principales: Ye, Xiang, An, Limei, Wang, Xiangxiang, Zhang, Chenyi, Huang, Wenqian, Sun, Chenggong, Li, Rongrong, Ma, Hanlin, Wang, Hongyan, Gao, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172172/
https://www.ncbi.nlm.nih.gov/pubmed/34094977
http://dx.doi.org/10.3389/fonc.2021.675104

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