Improved Decision-Making Confidence Using Item-Based Pharmacometric Model: Illustration with a Phase II Placebo-Controlled Trial

This study aimed to illustrate how a new methodology to assess clinical trial outcome measures using a longitudinal item response theory–based model (IRM) could serve as an alternative to mixed model repeated measures (MMRM). Data from the EXACT (Exacerbation of chronic pulmonary disease tool) which...

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Detalles Bibliográficos
Autores principales: Llanos-Paez, Carolina, Ambery, Claire, Yang, Shuying, Tabberer, Maggie, Beerahee, Misba, Plan, Elodie L., Karlsson, Mats O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172506/
https://www.ncbi.nlm.nih.gov/pubmed/34080077
http://dx.doi.org/10.1208/s12248-021-00600-1

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