An antibody against L1 cell adhesion molecule inhibits cardiotoxicity by regulating persistent DNA damage

Targeting the molecular pathways underlying the cardiotoxicity associated with thoracic irradiation and doxorubicin (Dox) could reduce the morbidity and mortality associated with these anticancer treatments. Here, we find that vascular endothelial cells (ECs) with persistent DNA damage induced by ir...

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Detalles Bibliográficos
Autores principales: Nam, Jae-Kyung, Kim, A-Ram, Choi, Seo-Hyun, Kim, Ji-Hee, Choi, Kyu Jin, Cho, Seulki, Lee, Jae Won, Cho, Hyun-Jai, Kwon, Yoo-Wook, Cho, Jaeho, Kim, Kwang Seok, Kim, Joon, Lee, Hae-June, Lee, Tae Sup, Bae, Sangwoo, Hong, Hyo Jeong, Lee, Yoon-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172563/
https://www.ncbi.nlm.nih.gov/pubmed/34078883
http://dx.doi.org/10.1038/s41467-021-23478-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172563/
https://www.ncbi.nlm.nih.gov/pubmed/34078883
http://dx.doi.org/10.1038/s41467-021-23478-1

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