Claudin-2 promotes colorectal cancer liver metastasis and is a biomarker of the replacement type growth pattern

Claudin-2 promotes breast cancer liver metastasis by enabling seeding and early cancer cell survival. We now demonstrate that Claudin-2 is functionally required for colorectal cancer liver metastasis and that Claudin-2 expression in primary colorectal cancers is associated with poor overall and live...

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Detalles Bibliográficos
Autores principales: Tabariès, Sébastien, Annis, Matthew G., Lazaris, Anthoula, Petrillo, Stephanie K., Huxham, Jennifer, Abdellatif, Amri, Palmieri, Vincent, Chabot, Jaclyn, Johnson, Radia M., Van Laere, Steven, Verhoef, Cornelis, Hachem, Yasmina, Yumeen, Sara, Meti, Nicholas, Omeroglu, Atilla, Altinel, Gulbeyaz, Gao, Zu-Hua, Yu, Alan S. L., Grünhagen, Dirk J., Vermeulen, Peter, Metrakos, Peter, Siegel, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8172859/
https://www.ncbi.nlm.nih.gov/pubmed/34079064
http://dx.doi.org/10.1038/s42003-021-02189-9

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