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GWAS Mediated Elucidation of Heterosis for Metric Traits in Cotton (Gossypium hirsutum L.) Across Multiple Environments

For about a century, plant breeding has widely exploited the heterosis phenomenon–often considered as hybrid vigor–to increase agricultural productivity. The ensuing F(1) hybrids can substantially outperform their progenitors due to heterozygous combinations that mitigate deleterious mutations occur...

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Autores principales: Sarfraz, Zareen, Iqbal, Muhammad Shahid, Geng, Xiaoli, Iqbal, Muhammad Sajid, Nazir, Mian Faisal, Ahmed, Haris, He, Shoupu, Jia, Yinhua, Pan, Zhaoe, Sun, Gaofei, Ahmad, Saghir, Wang, Qinglian, Qin, Hongde, Liu, Jinhai, Liu, Hui, Yang, Jun, Ma, Zhiying, Xu, Dongyong, Yang, Jinlong, Zhang, Jinbiao, Li, Zhikun, Cai, Zhongmin, Zhang, Xuelin, Zhang, Xin, Huang, Aifen, Yi, Xianda, Zhou, Guanyin, Li, Lin, Zhu, Haiyong, Pang, Baoyin, Wang, Liru, Sun, Junling, Du, Xiongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173050/
https://www.ncbi.nlm.nih.gov/pubmed/34093598
http://dx.doi.org/10.3389/fpls.2021.565552
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author Sarfraz, Zareen
Iqbal, Muhammad Shahid
Geng, Xiaoli
Iqbal, Muhammad Sajid
Nazir, Mian Faisal
Ahmed, Haris
He, Shoupu
Jia, Yinhua
Pan, Zhaoe
Sun, Gaofei
Ahmad, Saghir
Wang, Qinglian
Qin, Hongde
Liu, Jinhai
Liu, Hui
Yang, Jun
Ma, Zhiying
Xu, Dongyong
Yang, Jinlong
Zhang, Jinbiao
Li, Zhikun
Cai, Zhongmin
Zhang, Xuelin
Zhang, Xin
Huang, Aifen
Yi, Xianda
Zhou, Guanyin
Li, Lin
Zhu, Haiyong
Pang, Baoyin
Wang, Liru
Sun, Junling
Du, Xiongming
author_facet Sarfraz, Zareen
Iqbal, Muhammad Shahid
Geng, Xiaoli
Iqbal, Muhammad Sajid
Nazir, Mian Faisal
Ahmed, Haris
He, Shoupu
Jia, Yinhua
Pan, Zhaoe
Sun, Gaofei
Ahmad, Saghir
Wang, Qinglian
Qin, Hongde
Liu, Jinhai
Liu, Hui
Yang, Jun
Ma, Zhiying
Xu, Dongyong
Yang, Jinlong
Zhang, Jinbiao
Li, Zhikun
Cai, Zhongmin
Zhang, Xuelin
Zhang, Xin
Huang, Aifen
Yi, Xianda
Zhou, Guanyin
Li, Lin
Zhu, Haiyong
Pang, Baoyin
Wang, Liru
Sun, Junling
Du, Xiongming
author_sort Sarfraz, Zareen
collection PubMed
description For about a century, plant breeding has widely exploited the heterosis phenomenon–often considered as hybrid vigor–to increase agricultural productivity. The ensuing F(1) hybrids can substantially outperform their progenitors due to heterozygous combinations that mitigate deleterious mutations occurring in each genome. However, only fragmented knowledge is available concerning the underlying genes and processes that foster heterosis. Although cotton is among the highly valued crops, its improvement programs that involve the exploitation of heterosis are still limited in terms of significant accomplishments to make it broadly applicable in different agro-ecological zones. Here, F(1) hybrids were derived from mating a diverse Upland Cotton germplasm with commercially valuable cultivars in the Line × Tester fashion and evaluated across multiple environments for 10 measurable traits. These traits were dissected into five different heterosis types and specific combining ability (SCA). Subsequent genome-wide predictions along-with association analyses uncovered a set of 298 highly significant key single nucleotide polymorphisms (SNPs)/Quantitative Trait Nucleotides (QTNs) and 271 heterotic Quantitative Trait Nucleotides (hQTNs) related to agronomic and fiber quality traits. The integration of a genome wide association study with RNA-sequence analysis yielded 275 candidate genes in the vicinity of key SNPs/QTNs. Fiber micronaire (MIC) and lint percentage (LP) had the maximum number of associated genes, i.e., each with 45 related to QTNs/hQTNs. A total of 54 putative candidate genes were identified in association with HETEROSIS of quoted traits. The novel players in the heterosis mechanism highlighted in this study may prove to be scientifically and biologically important for cotton biologists, and for those breeders engaged in cotton fiber and yield improvement programs.
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spelling pubmed-81730502021-06-04 GWAS Mediated Elucidation of Heterosis for Metric Traits in Cotton (Gossypium hirsutum L.) Across Multiple Environments Sarfraz, Zareen Iqbal, Muhammad Shahid Geng, Xiaoli Iqbal, Muhammad Sajid Nazir, Mian Faisal Ahmed, Haris He, Shoupu Jia, Yinhua Pan, Zhaoe Sun, Gaofei Ahmad, Saghir Wang, Qinglian Qin, Hongde Liu, Jinhai Liu, Hui Yang, Jun Ma, Zhiying Xu, Dongyong Yang, Jinlong Zhang, Jinbiao Li, Zhikun Cai, Zhongmin Zhang, Xuelin Zhang, Xin Huang, Aifen Yi, Xianda Zhou, Guanyin Li, Lin Zhu, Haiyong Pang, Baoyin Wang, Liru Sun, Junling Du, Xiongming Front Plant Sci Plant Science For about a century, plant breeding has widely exploited the heterosis phenomenon–often considered as hybrid vigor–to increase agricultural productivity. The ensuing F(1) hybrids can substantially outperform their progenitors due to heterozygous combinations that mitigate deleterious mutations occurring in each genome. However, only fragmented knowledge is available concerning the underlying genes and processes that foster heterosis. Although cotton is among the highly valued crops, its improvement programs that involve the exploitation of heterosis are still limited in terms of significant accomplishments to make it broadly applicable in different agro-ecological zones. Here, F(1) hybrids were derived from mating a diverse Upland Cotton germplasm with commercially valuable cultivars in the Line × Tester fashion and evaluated across multiple environments for 10 measurable traits. These traits were dissected into five different heterosis types and specific combining ability (SCA). Subsequent genome-wide predictions along-with association analyses uncovered a set of 298 highly significant key single nucleotide polymorphisms (SNPs)/Quantitative Trait Nucleotides (QTNs) and 271 heterotic Quantitative Trait Nucleotides (hQTNs) related to agronomic and fiber quality traits. The integration of a genome wide association study with RNA-sequence analysis yielded 275 candidate genes in the vicinity of key SNPs/QTNs. Fiber micronaire (MIC) and lint percentage (LP) had the maximum number of associated genes, i.e., each with 45 related to QTNs/hQTNs. A total of 54 putative candidate genes were identified in association with HETEROSIS of quoted traits. The novel players in the heterosis mechanism highlighted in this study may prove to be scientifically and biologically important for cotton biologists, and for those breeders engaged in cotton fiber and yield improvement programs. Frontiers Media S.A. 2021-05-20 /pmc/articles/PMC8173050/ /pubmed/34093598 http://dx.doi.org/10.3389/fpls.2021.565552 Text en Copyright © 2021 Sarfraz, Iqbal, Geng, Iqbal, Nazir, Ahmed, He, Jia, Pan, Sun, Ahmad, Wang, Qin, Liu, Liu, Yang, Ma, Xu, Yang, Zhang, Li, Cai, Zhang, Zhang, Huang, Yi, Zhou, Li, Zhu, Pang, Wang, Sun and Du. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Plant Science
Sarfraz, Zareen
Iqbal, Muhammad Shahid
Geng, Xiaoli
Iqbal, Muhammad Sajid
Nazir, Mian Faisal
Ahmed, Haris
He, Shoupu
Jia, Yinhua
Pan, Zhaoe
Sun, Gaofei
Ahmad, Saghir
Wang, Qinglian
Qin, Hongde
Liu, Jinhai
Liu, Hui
Yang, Jun
Ma, Zhiying
Xu, Dongyong
Yang, Jinlong
Zhang, Jinbiao
Li, Zhikun
Cai, Zhongmin
Zhang, Xuelin
Zhang, Xin
Huang, Aifen
Yi, Xianda
Zhou, Guanyin
Li, Lin
Zhu, Haiyong
Pang, Baoyin
Wang, Liru
Sun, Junling
Du, Xiongming
GWAS Mediated Elucidation of Heterosis for Metric Traits in Cotton (Gossypium hirsutum L.) Across Multiple Environments
title GWAS Mediated Elucidation of Heterosis for Metric Traits in Cotton (Gossypium hirsutum L.) Across Multiple Environments
title_full GWAS Mediated Elucidation of Heterosis for Metric Traits in Cotton (Gossypium hirsutum L.) Across Multiple Environments
title_fullStr GWAS Mediated Elucidation of Heterosis for Metric Traits in Cotton (Gossypium hirsutum L.) Across Multiple Environments
title_full_unstemmed GWAS Mediated Elucidation of Heterosis for Metric Traits in Cotton (Gossypium hirsutum L.) Across Multiple Environments
title_short GWAS Mediated Elucidation of Heterosis for Metric Traits in Cotton (Gossypium hirsutum L.) Across Multiple Environments
title_sort gwas mediated elucidation of heterosis for metric traits in cotton (gossypium hirsutum l.) across multiple environments
topic Plant Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173050/
https://www.ncbi.nlm.nih.gov/pubmed/34093598
http://dx.doi.org/10.3389/fpls.2021.565552
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