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Personalized medicine modality based on patient-derived xenografts from a malignant transformed GCTB harboring H3F3A G34W mutation

BACKGROUND: The function of H3F3A G43W mutation, which has been observed in almost all GCTB, remains poorly characterized. Breakthrough in malignant GCTB has been trapped by the lack of clinical available drugs, limited canonical patient samples and paucity of fidelity preclinical models. METHODS: T...

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Detalles Bibliográficos
Autores principales:	Yafei, Jiang, Haoran, Mu, Wenyan, Jiang, Linghang, Xue, Kai, Tian, Gangyang, Wang, Zhuoying, Wang, Jing, Han, Mengkai, Yang, Yujie, Tang, Yingqi, Hua, Zhengdong, Cai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Chinese Speaking Orthopaedic Society 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173097/ https://www.ncbi.nlm.nih.gov/pubmed/34136349 http://dx.doi.org/10.1016/j.jot.2021.04.004

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