Macrophage LAMTOR1 Deficiency Prevents Dietary Obesity and Insulin Resistance Through Inflammation-Induced Energy Expenditure

Here, we studied the metabolic function of LAMTOR1 from macrophages using LAMTOR1 macrophage-specific knockout (MKO) mice. LAMTOR1 MKO mice showed resistance to high-fat diet (HFD)-induced obesity, lipid steatosis, and glucose metabolic disorders, with elevated levels of pro-inflammatory cytokines....

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Detalles Bibliográficos
Autores principales: Ying, Lingwen, Zhang, Mingliang, Ma, Xiaojing, Si, Yiming, Li, Xiaoya, Su, Jiaorong, Yin, Jun, Bao, Yuqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173123/
https://www.ncbi.nlm.nih.gov/pubmed/34095141
http://dx.doi.org/10.3389/fcell.2021.672032

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