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Loss of Pde6a Induces Rod Outer Segment Shrinkage and Visual Alterations in pde6a(Q70X) Mutant Zebrafish, a Relevant Model of Retinal Dystrophy
Retinitis pigmentosa (RP) is one of the most common forms of inherited retinal degeneration with 1/4,000 people being affected. The vision alteration primarily begins with rod photoreceptor degeneration, then the degenerative process continues with cone photoreceptor death. Variants in 71 genes have...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173125/ https://www.ncbi.nlm.nih.gov/pubmed/34095146 http://dx.doi.org/10.3389/fcell.2021.675517 |