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Pericardial Diseases in COVID19: a Contemporary Review

PURPOSE OF REVIEW: Coronavirus disease 2019 (COVID19) involves the heart, including pericardium. This article reviews the possible pathophysiological mechanisms in pericardial involvement in COVID19 and pericardial manifestations of COVID19. It also summarizes the patients with pericarditis secondar...

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Autores principales: Furqan, Muhammad M., Verma, Beni R., Cremer, Paul C., Imazio, Massimo, Klein, Allan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173318/
https://www.ncbi.nlm.nih.gov/pubmed/34081219
http://dx.doi.org/10.1007/s11886-021-01519-x
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author Furqan, Muhammad M.
Verma, Beni R.
Cremer, Paul C.
Imazio, Massimo
Klein, Allan L.
author_facet Furqan, Muhammad M.
Verma, Beni R.
Cremer, Paul C.
Imazio, Massimo
Klein, Allan L.
author_sort Furqan, Muhammad M.
collection PubMed
description PURPOSE OF REVIEW: Coronavirus disease 2019 (COVID19) involves the heart, including pericardium. This article reviews the possible pathophysiological mechanisms in pericardial involvement in COVID19 and pericardial manifestations of COVID19. It also summarizes the patients with pericarditis secondary to COVID19 and outlines the contemporary treatment strategies in this patient population. RECENT FINDINGS: A high degree of suspicion is required to identify the pericardial involvement in COVID19 patients. It is proposed that an underlying hyperinflammatory reaction in COVID19 leads to pericardial inflammation. Acute pericarditis with or without myocardial involvement is diagnosed on clinical presentation, serum inflammatory markers, electrocardiogram, and echocardiogram. Multimodality imaging may also have an additional diagnostic value. Patients are usually managed medically, but some patients develop a life-threatening pericardial tamponade necessitating pericardial drainage. SUMMARY: Pericardial involvement is an important clinical manifestation of COVID19 requiring a proper workup. Timely diagnosis and a specific management plan based on the presentation and concomitant organ involvement usually lead to a complete recovery.
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spelling pubmed-81733182021-06-03 Pericardial Diseases in COVID19: a Contemporary Review Furqan, Muhammad M. Verma, Beni R. Cremer, Paul C. Imazio, Massimo Klein, Allan L. Curr Cardiol Rep Pericardial Disease (AL Klein and CL Jellis, Section Editors) PURPOSE OF REVIEW: Coronavirus disease 2019 (COVID19) involves the heart, including pericardium. This article reviews the possible pathophysiological mechanisms in pericardial involvement in COVID19 and pericardial manifestations of COVID19. It also summarizes the patients with pericarditis secondary to COVID19 and outlines the contemporary treatment strategies in this patient population. RECENT FINDINGS: A high degree of suspicion is required to identify the pericardial involvement in COVID19 patients. It is proposed that an underlying hyperinflammatory reaction in COVID19 leads to pericardial inflammation. Acute pericarditis with or without myocardial involvement is diagnosed on clinical presentation, serum inflammatory markers, electrocardiogram, and echocardiogram. Multimodality imaging may also have an additional diagnostic value. Patients are usually managed medically, but some patients develop a life-threatening pericardial tamponade necessitating pericardial drainage. SUMMARY: Pericardial involvement is an important clinical manifestation of COVID19 requiring a proper workup. Timely diagnosis and a specific management plan based on the presentation and concomitant organ involvement usually lead to a complete recovery. Springer US 2021-06-03 2021 /pmc/articles/PMC8173318/ /pubmed/34081219 http://dx.doi.org/10.1007/s11886-021-01519-x Text en © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Pericardial Disease (AL Klein and CL Jellis, Section Editors)
Furqan, Muhammad M.
Verma, Beni R.
Cremer, Paul C.
Imazio, Massimo
Klein, Allan L.
Pericardial Diseases in COVID19: a Contemporary Review
title Pericardial Diseases in COVID19: a Contemporary Review
title_full Pericardial Diseases in COVID19: a Contemporary Review
title_fullStr Pericardial Diseases in COVID19: a Contemporary Review
title_full_unstemmed Pericardial Diseases in COVID19: a Contemporary Review
title_short Pericardial Diseases in COVID19: a Contemporary Review
title_sort pericardial diseases in covid19: a contemporary review
topic Pericardial Disease (AL Klein and CL Jellis, Section Editors)
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173318/
https://www.ncbi.nlm.nih.gov/pubmed/34081219
http://dx.doi.org/10.1007/s11886-021-01519-x
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