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Primary primitive neuroectodermal tumor in the pericardium—a focus on imaging findings: A case report

BACKGROUND: Primitive neuroectodermal tumors (PNETs) are rare, sporadic malignant tumors of the peripheral nervous system, bone, or soft tissues. However, to the best of our knowledge, only three cases of PNET in the pericardium have been reported in the English literature, and their magnetic resona...

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Autores principales: Xu, Shu-Ming, Bai, Juan, Cai, Jin-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173412/
https://www.ncbi.nlm.nih.gov/pubmed/34141798
http://dx.doi.org/10.12998/wjcc.v9.i17.4336
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author Xu, Shu-Ming
Bai, Juan
Cai, Jin-Hua
author_facet Xu, Shu-Ming
Bai, Juan
Cai, Jin-Hua
author_sort Xu, Shu-Ming
collection PubMed
description BACKGROUND: Primitive neuroectodermal tumors (PNETs) are rare, sporadic malignant tumors of the peripheral nervous system, bone, or soft tissues. However, to the best of our knowledge, only three cases of PNET in the pericardium have been reported in the English literature, and their magnetic resonance imaging findings have not previously been described. CASE SUMMARY: A 3-year-old boy was hospitalized with a 1-wk history of recurrent vomiting and weakness. Detailed history-taking revealed no evidence of heart disease. Computed tomography demonstrated a soft tissue mass in the left pericardial cavity with heterogeneous contrast enhancement. The border between the mass and the heart was poorly defined. Thoracotomy revealed a mass invading the left ventricle, with a high risk of bleeding. The mass was considered inoperable. A biopsy was performed, and the histological and immunohistochemical findings confirmed the diagnosis of primary PNET of the pericardium. The patient received four cycles of standard chemotherapy. Chest magnetic resonance imaging 3 mo after the initiation of chemotherapy revealed that the tumor in the pericardium still existed, but its volume had slightly decreased. The patient was lost to follow-up, and the final outcome was therefore unknown. CONCLUSION: Medical imaging plays an important role in defining the pericardial origin of PNET and understanding its characteristics. Magnetic resonance imaging can provide more information on the tumor than computed tomography and may thus aid therapeutic planning.
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spelling pubmed-81734122021-06-16 Primary primitive neuroectodermal tumor in the pericardium—a focus on imaging findings: A case report Xu, Shu-Ming Bai, Juan Cai, Jin-Hua World J Clin Cases Case Report BACKGROUND: Primitive neuroectodermal tumors (PNETs) are rare, sporadic malignant tumors of the peripheral nervous system, bone, or soft tissues. However, to the best of our knowledge, only three cases of PNET in the pericardium have been reported in the English literature, and their magnetic resonance imaging findings have not previously been described. CASE SUMMARY: A 3-year-old boy was hospitalized with a 1-wk history of recurrent vomiting and weakness. Detailed history-taking revealed no evidence of heart disease. Computed tomography demonstrated a soft tissue mass in the left pericardial cavity with heterogeneous contrast enhancement. The border between the mass and the heart was poorly defined. Thoracotomy revealed a mass invading the left ventricle, with a high risk of bleeding. The mass was considered inoperable. A biopsy was performed, and the histological and immunohistochemical findings confirmed the diagnosis of primary PNET of the pericardium. The patient received four cycles of standard chemotherapy. Chest magnetic resonance imaging 3 mo after the initiation of chemotherapy revealed that the tumor in the pericardium still existed, but its volume had slightly decreased. The patient was lost to follow-up, and the final outcome was therefore unknown. CONCLUSION: Medical imaging plays an important role in defining the pericardial origin of PNET and understanding its characteristics. Magnetic resonance imaging can provide more information on the tumor than computed tomography and may thus aid therapeutic planning. Baishideng Publishing Group Inc 2021-06-16 2021-06-16 /pmc/articles/PMC8173412/ /pubmed/34141798 http://dx.doi.org/10.12998/wjcc.v9.i17.4336 Text en ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
spellingShingle Case Report
Xu, Shu-Ming
Bai, Juan
Cai, Jin-Hua
Primary primitive neuroectodermal tumor in the pericardium—a focus on imaging findings: A case report
title Primary primitive neuroectodermal tumor in the pericardium—a focus on imaging findings: A case report
title_full Primary primitive neuroectodermal tumor in the pericardium—a focus on imaging findings: A case report
title_fullStr Primary primitive neuroectodermal tumor in the pericardium—a focus on imaging findings: A case report
title_full_unstemmed Primary primitive neuroectodermal tumor in the pericardium—a focus on imaging findings: A case report
title_short Primary primitive neuroectodermal tumor in the pericardium—a focus on imaging findings: A case report
title_sort primary primitive neuroectodermal tumor in the pericardium—a focus on imaging findings: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173412/
https://www.ncbi.nlm.nih.gov/pubmed/34141798
http://dx.doi.org/10.12998/wjcc.v9.i17.4336
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