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Deleterious mutation V369M in the mouse GCGR gene causes abnormal plasma amino acid levels indicative of a possible liver–α-cell axis

Glucagon plays an important role in glucose homeostasis and amino acid metabolism. It regulates plasma amino acid levels which in turn modulate glucagon secretion from the pancreatic α-cell, thereby establishing a liver–α-cell axis described recently. We reported previously that the knock-in mice be...

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Detalles Bibliográficos
Autores principales:	Liu, Qiaofeng, Lin, Guangyao, Chen, Yan, Feng, Wenbo, Xu, Yingna, Lyu, Jianjun, Yang, Dehua, Wang, Ming-Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2021
Materias:	Diabetes & Metabolic Disorders
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173527/ https://www.ncbi.nlm.nih.gov/pubmed/34002801 http://dx.doi.org/10.1042/BSR20210758

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