Cargando…

Design of New Schiff-Base Copper(II) Complexes: Synthesis, Crystal Structures, DFT Study, and Binding Potency toward Cytochrome P450 3A4

[Image: see text] We report the synthesis and crystal structures of three new copper(II) Schiff-base complexes. The complexes have been characterized by elemental analysis and Fourier transform infrared (FT-IR) and UV–visible spectroscopies. The X-ray diffraction (XRD) analysis reveals that complexe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yusuf, Tunde L., Oladipo, Segun D., Zamisa, Sizwe, Kumalo, Hezekiel M., Lawal, Isiaka A., Lawal, Monsurat M., Mabuba, Nonhlangabezo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173565/ https://www.ncbi.nlm.nih.gov/pubmed/34095663 http://dx.doi.org/10.1021/acsomega.1c00906

Ejemplares similares

Ni(2+) and Cu(2+) complexes of N-(2,6-dichlorophenyl)-N-mesityl formamidine dithiocarbamate structural and functional properties as CYP3A4 potential substrates
por: Oladipo, Segun D., et al.
Publicado: (2023)

Allostery Inhibition of BACE1 by Psychotic and Meroterpenoid Drugs in Alzheimer’s Disease Therapy
por: Ugbaja, Samuel C., et al.
Publicado: (2022)

Drug Discovery for Mycobacterium tuberculosis Using Structure-Based Computer-Aided Drug Design Approach
por: Ejalonibu, Murtala A., et al.
Publicado: (2021)

Influenza Viruses: Harnessing the Crucial Role of the M2 Ion-Channel and Neuraminidase toward Inhibitor Design
por: Mtambo, Sphamadla E., et al.
Publicado: (2021)

The application of photoelectrocatalysis in the degradation of rhodamine B in aqueous solutions: a review
por: Yusuf, Tunde Lewis, et al.
Publicado: (2022)

Secondary metabolites produced by endophytic fungi, Alternaria alternata, as potential inhibitors of the human immunodeficiency virus
por: Nzimande, Bruce, et al.
Publicado: (2022)

Understanding the Hsp90 N-Terminal Dynamics: Structural and Molecular Insights into the Therapeutic Activities of Anticancer Inhibitors Radicicol (RD) and Radicicol Derivative (NVP-YUA922)
por: Magwenyane, Ayanda M., et al.
Publicado: (2020)

Epigenetic Induction of Secondary Metabolites Production in Endophytic Fungi Penicillium chrysogenum and GC-MS Analysis of Crude Metabolites with Anti-HIV-1 Activity
por: Makhwitine, John P., et al.
Publicado: (2023)

Quinoline Functionalized Schiff Base Silver (I) Complexes: Interactions with Biomolecules and In Vitro Cytotoxicity, Antioxidant and Antimicrobial Activities
por: Adeleke, Adesola A., et al.
Publicado: (2021)

Carbon Nanodots Embedded on a Polyethersulfone Membrane for Cadmium(II) Removal from Water
por: Sam, Simanye, et al.
Publicado: (2021)

An Exfoliated Graphite-Based Electrochemical Immunosensor on a Dendrimer/Carbon Nanodot Platform for the Detection of Carcinoembryonic Antigen Cancer Biomarker
por: Idris, Azeez O., et al.
Publicado: (2019)

Towards cancer diagnostics – an α-feto protein electrochemical immunosensor on a manganese(iv) oxide/gold nanocomposite immobilisation layer
por: Idris, Azeez O., et al.
Publicado: (2018)

Sonoelectrochemical oxidation of sulfamethoxazole in simulated and actual wastewater on a piezo-polarizable FTO/BaZr(x)Ti((1−x))O(3) electrode: reaction kinetics, mechanism and reaction pathway studies
por: Ojo, Babatope O., et al.
Publicado: (2022)

Computational studies of potential antiviral compounds from some selected Nigerian medicinal plants against SARS-CoV-2 proteins
por: Ibeh, Raymond C., et al.
Publicado: (2023)

Thin Films (FTO/BaTiO(3)/AgNPs) for Enhanced Piezo-Photocatalytic Degradation of Methylene Blue and Ciprofloxacin in Wastewater
por: Masekela, Daniel, et al.
Publicado: (2022)

Oxidation of Styrene to Benzaldehyde Catalyzed by Schiff Base Functionalized Triazolylidene Ni(II) Complexes
por: Lawal, Nasir S., et al.
Publicado: (2022)

In Silico Drug Repurposing of FDA-Approved Drugs Highlighting Promacta as a Potential Inhibitor of H7N9 Influenza Virus
por: Mtambo, Sphamandla E., et al.
Publicado: (2022)

The Role of ATP Hydrolysis and Product Release in the Translocation Mechanism of SARS-CoV-2 NSP13
por: Lawal, Monsurat M., et al.
Publicado: (2023)

l-Isoleucine-Schiff Base Copper(II) Coordination Polymers: Crystal Structure, Spectroscopic, Hirshfeld Surface, and DFT Analyses
por: Chavez-Urias, Iván F., et al.
Publicado: (2023)

Effects and Mechanism of Nano-Copper Exposure on Hepatic Cytochrome P450 Enzymes in Rats
por: Tang, Huaqiao, et al.
Publicado: (2018)

The Cytochrome P450 Homepage
por: Nelson, David R
Publicado: (2009)

Probing the Role of the Hinge Segment of Cytochrome P450 Oxidoreductase in the Interaction with Cytochrome P450
por: Campelo, Diana, et al.
Publicado: (2018)

The FMN “140s Loop” of Cytochrome P450 Reductase Controls Electron Transfer to Cytochrome P450
por: Rwere, Freeborn, et al.
Publicado: (2021)

Theory and Applications of Covalent Docking in Drug Discovery: Merits and Pitfalls
por: Kumalo, Hezekiel Mathambo, et al.
Publicado: (2015)

Mechanism of Inhibition of Hsp90 Dimerization by Gyrase B Inhibitor Coumermycin A1 (C–A1) Revealed by Molecular Dynamics Simulations and Thermodynamic Calculations
por: Cele, Favourite N., et al.
Publicado: (2016)

A Brief Overview of the Microstructural Engineering of Inorganic–Organic Composite Membranes Derived from Organic Chelating Ligands
por: Lawal, Sulaiman Oladipo, et al.
Publicado: (2023)

Fungal cytochrome P450 database
por: Park, Jongsun, et al.
Publicado: (2008)

Cytochrome P450 humanised mice
por: Gonzalez, Frank J
Publicado: (2004)

Intronic polymorphisms of cytochromes P450
por: Ingelman-Sundberg, Magnus, et al.
Publicado: (2010)

The Role of Cytochromes P450 in Infection
por: Stavropoulou, Elisavet, et al.
Publicado: (2018)

Cytochromes P450, Oxygen, and Evolution
por: Lewis, David F.V., et al.
Publicado: (2001)

Correlation of Cytochrome P450 Oxidoreductase Expression with the Expression of 10 Isoforms of Cytochrome P450 in Human Liver
por: Zhang, Hai-Feng, et al.
Publicado: (2016)

1-Aminobenzotriazole: A Mechanism-Based Cytochrome P450 Inhibitor and Probe of Cytochrome P450 Biology
por: de Montellano, Paul R Ortiz
Publicado: (2018)

Allosteric modulation of cytochrome P450 enzymes by the NADPH cytochrome P450 reductase FMN-containing domain
por: Burris-Hiday, Sarah D., et al.
Publicado: (2023)

Impact of the R292K Mutation on Influenza A (H7N9) Virus Resistance towards Peramivir: A Molecular Dynamics Perspective
por: Mtambo, Sphamandla E., et al.
Publicado: (2022)

Synthesis, characterization, DFT calculations and biological activity of new Schiff base complexes
por: Alkhatib, Fatmah M., et al.
Publicado: (2023)

Cytochrome P450-Mediated Phytoremediation using Transgenic Plants: A Need for Engineered Cytochrome P450 Enzymes
por: Kumar, Santosh, et al.
Publicado: (2012)

Drug therapy-related problem management in Nigeria community pharmacy – process evaluation with simulated patient
por: Segun, Showande Johnson, et al.
Publicado: (2022)

Potential inhibition of major human cytochrome P450 isoenzymes by selected tropical medicinal herbs—Implication for herb–drug interactions
por: Showande, Segun Johnson, et al.
Publicado: (2018)

Fungal Cytochrome P450s and the P450 Complement (CYPome) of Fusarium graminearum
por: Shin, Jiyoung, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_dfhhmo20logiscktqili7o532e