Fungally Derived Isoquinoline Demonstrates Inducer-Specific Tau Aggregation Inhibition

[Image: see text] The microtubule-associated protein tau promotes the stabilization of the axonal cytoskeleton in neurons. In several neurodegenerative diseases, such as Alzheimer’s disease, tau has been found to dissociate from microtubules, leading to the formation of pathological aggregates that...

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Detalles Bibliográficos
Autores principales: Ingham, David J., Blankenfeld, Bryce R., Chacko, Shibin, Perera, Chamani, Oakley, Berl R., Gamblin, Truman Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173610/
https://www.ncbi.nlm.nih.gov/pubmed/34009955
http://dx.doi.org/10.1021/acs.biochem.1c00111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173610/
https://www.ncbi.nlm.nih.gov/pubmed/34009955
http://dx.doi.org/10.1021/acs.biochem.1c00111

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