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Fungally Derived Isoquinoline Demonstrates Inducer-Specific Tau Aggregation Inhibition
[Image: see text] The microtubule-associated protein tau promotes the stabilization of the axonal cytoskeleton in neurons. In several neurodegenerative diseases, such as Alzheimer’s disease, tau has been found to dissociate from microtubules, leading to the formation of pathological aggregates that...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173610/ https://www.ncbi.nlm.nih.gov/pubmed/34009955 http://dx.doi.org/10.1021/acs.biochem.1c00111 |