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Single Molecule–Based fliFISH Validates Radial and Heterogeneous Gene Expression Patterns in Pancreatic Islet β-Cells

Single-cell RNA-sequencing (scRNA-Seq) technologies have greatly enhanced our understanding of islet cell transcriptomes and have revealed the existence of β-cell heterogeneity. However, comparison of scRNA-Seq data sets from different groups have highlighted inconsistencies in gene expression patte...

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Detalles Bibliográficos
Autores principales: Li, Fangjia, Hu, Dehong, Dieter, Cailin, Ansong, Charles, Sussel, Lori, Orr, Galya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173798/
https://www.ncbi.nlm.nih.gov/pubmed/33685924
http://dx.doi.org/10.2337/db20-0802